A Case of Acute Eosinophilic Pneumonia Following Short-Term Passive Smoking: An Evidence of Very High Level of Urinary Cotinine
Acute eosinophilic pneumonia (AEP) is characterized by febrile illness, diffuse pulmonary infiltrates with eosinophilia. The pathogenesis is not well understood. We report a case of 22-year-old men who never smoke presented with AEP 2 days after acute passive smoke exposure. He developed acute respi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2010-01-01
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| Series: | Allergology International |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1323893015306559 |
| _version_ | 1818882879659180032 |
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| author | Kosaku Komiya Shinji Teramoto Masahiro Kawashima Yuichiro Kurosaki Shunsuke Shoji Akira Hebisawa |
| author_facet | Kosaku Komiya Shinji Teramoto Masahiro Kawashima Yuichiro Kurosaki Shunsuke Shoji Akira Hebisawa |
| author_sort | Kosaku Komiya |
| collection | DOAJ |
| description | Acute eosinophilic pneumonia (AEP) is characterized by febrile illness, diffuse pulmonary infiltrates with eosinophilia. The pathogenesis is not well understood. We report a case of 22-year-old men who never smoke presented with AEP 2 days after acute passive smoke exposure. He developed acute respiratory failure despite having no history of the disease. Computed tomography of the lung revealed diffuse bilateral pulmonary infiltrates. Lung biopsy specimens revealed marked eosinophil infiltration in the alveolar septa without signs of vasculitis.
Two days prior to the disease, he was exposed to cigarette smoke for 2 hours in a closed area. In the absence of other causes, passive smoking may cause lung inflammatory responses.
The level of urinary cotinine, which is a biomarker of smoke exposure, was considerably higher (0.198 μg/ml [201 ng/mg Creatinine]) than that in nonsmokers, but never detected following period. This case suggests that short-term passive smoking may cause AEP. |
| first_indexed | 2024-12-19T15:24:46Z |
| format | Article |
| id | doaj.art-bb411bbbac634d6bb41b215b51d49b99 |
| institution | Directory Open Access Journal |
| issn | 1323-8930 |
| language | English |
| last_indexed | 2024-12-19T15:24:46Z |
| publishDate | 2010-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Allergology International |
| spelling | doaj.art-bb411bbbac634d6bb41b215b51d49b992022-12-21T20:15:55ZengElsevierAllergology International1323-89302010-01-0159442142310.2332/allergolint.10-CR-0203A Case of Acute Eosinophilic Pneumonia Following Short-Term Passive Smoking: An Evidence of Very High Level of Urinary CotinineKosaku Komiya0Shinji Teramoto1Masahiro Kawashima2Yuichiro Kurosaki3Shunsuke Shoji4Akira Hebisawa5Department of Pulmonary Medicine, Tokyo, Japan.Department of Pulmonary Medicine, Tokyo, Japan.Department of Pulmonary Medicine, Tokyo, Japan.Department of Pulmonary Medicine, Tokyo, Japan.Department of Allergy, Tokyo, Japan.Department of Pathology, National Hospital Organization, Tokyo National Hospital, Tokyo, Japan.Acute eosinophilic pneumonia (AEP) is characterized by febrile illness, diffuse pulmonary infiltrates with eosinophilia. The pathogenesis is not well understood. We report a case of 22-year-old men who never smoke presented with AEP 2 days after acute passive smoke exposure. He developed acute respiratory failure despite having no history of the disease. Computed tomography of the lung revealed diffuse bilateral pulmonary infiltrates. Lung biopsy specimens revealed marked eosinophil infiltration in the alveolar septa without signs of vasculitis. Two days prior to the disease, he was exposed to cigarette smoke for 2 hours in a closed area. In the absence of other causes, passive smoking may cause lung inflammatory responses. The level of urinary cotinine, which is a biomarker of smoke exposure, was considerably higher (0.198 μg/ml [201 ng/mg Creatinine]) than that in nonsmokers, but never detected following period. This case suggests that short-term passive smoking may cause AEP.http://www.sciencedirect.com/science/article/pii/S1323893015306559acute eosinophilic pneumoniaacute respiratory distress syndromelung biopsy specimenspassive smokingurinary cotinine |
| spellingShingle | Kosaku Komiya Shinji Teramoto Masahiro Kawashima Yuichiro Kurosaki Shunsuke Shoji Akira Hebisawa A Case of Acute Eosinophilic Pneumonia Following Short-Term Passive Smoking: An Evidence of Very High Level of Urinary Cotinine Allergology International acute eosinophilic pneumonia acute respiratory distress syndrome lung biopsy specimens passive smoking urinary cotinine |
| title | A Case of Acute Eosinophilic Pneumonia Following Short-Term Passive Smoking: An Evidence of Very High Level of Urinary Cotinine |
| title_full | A Case of Acute Eosinophilic Pneumonia Following Short-Term Passive Smoking: An Evidence of Very High Level of Urinary Cotinine |
| title_fullStr | A Case of Acute Eosinophilic Pneumonia Following Short-Term Passive Smoking: An Evidence of Very High Level of Urinary Cotinine |
| title_full_unstemmed | A Case of Acute Eosinophilic Pneumonia Following Short-Term Passive Smoking: An Evidence of Very High Level of Urinary Cotinine |
| title_short | A Case of Acute Eosinophilic Pneumonia Following Short-Term Passive Smoking: An Evidence of Very High Level of Urinary Cotinine |
| title_sort | case of acute eosinophilic pneumonia following short term passive smoking an evidence of very high level of urinary cotinine |
| topic | acute eosinophilic pneumonia acute respiratory distress syndrome lung biopsy specimens passive smoking urinary cotinine |
| url | http://www.sciencedirect.com/science/article/pii/S1323893015306559 |
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