Microanatomic Morphometric Characteristics of the Third Ventricle Floor
<b>Background</b>: Endoscopic third ventriculostomy (ETV) is an effective treatment for hydrocephalus. The in-depth understanding of microanatomy is essential for accurate diagnosis, treatment and complications prevention. The aim of this study is to supplement the knowledge gap regardin...
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MDPI AG
2023-03-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/13/4/580 |
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| author | Marios Theologou Konstantinos Kouskouras Konstantinos Natsis Panagiotis Varoutis Eleni Zaggelidou Christos Tsonidis |
| author_facet | Marios Theologou Konstantinos Kouskouras Konstantinos Natsis Panagiotis Varoutis Eleni Zaggelidou Christos Tsonidis |
| author_sort | Marios Theologou |
| collection | DOAJ |
| description | <b>Background</b>: Endoscopic third ventriculostomy (ETV) is an effective treatment for hydrocephalus. The in-depth understanding of microanatomy is essential for accurate diagnosis, treatment and complications prevention. The aim of this study is to supplement the knowledge gap regarding the microanatomical metrics and correlations for which the literature includes only scarce mentions at best. <b>Methods:</b> This is a descriptive microanatomical study including 25 cadaver brains. Specimens from donors with neurological, psychiatric disorders or alcohol abuse were excluded. Surgical loops were used for harvesting. High-precision tools were employed to dissect and measure the anatomical landmarks under a surgical microscope. Each measurement was performed in three consecutive attempts and outliers were rejected. RStudio was used for statistical analysis. Distribution was evaluated employing the Shapiro–Wilk test. Normally distributed values were presented as mean and standard deviation, and others as median and interquartile range. <b>Results:</b> The age of the donors was 61.72 (±10.08) years. The distance from the anterior aspect of the foramen of Monro to the anterior margin of the mamillary body was 16.83 (±1.04) mm, and to the posterior margin was 16.76 (±1.9) mm. The distance from the anterior mamillary body margin to the infundibulum was 6.39 (±1.9) mm, to the optic recess was 8.25 (±1.84) mm, and to the apex of the vertebral artery was 5.05 (±1.62) mm. The distance from the anterior commissure to the brain aqueduct was 22.46 (±2.29) mm, and to the infundibulum was 13.93 (±2.54) mm. The mamillary body diameter was 4.91 (±0.34) mm in the anteroposterior and 4.21 (±0.48) mm in the cranio-caudal plane. The intraventricular segment was protruding by 1.63 (±0.46) mm. The diameter of the hypothalamus on the anterior margin of mamillary bodies was 1.37 (±0.75) mm, of the Liliequist membrane was 0.19 (±0.07) mm and of the lamina terminalis was 0.35 (±0.32) mm. <b>Conclusion:</b> The presented microanatomical measurements and correlations are expected to contribute to the improvement of ETV safety. |
| first_indexed | 2024-03-11T05:12:19Z |
| format | Article |
| id | doaj.art-bb4f52f0e1884e39ba221f702b37778a |
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| language | English |
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| publishDate | 2023-03-01 |
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| spelling | doaj.art-bb4f52f0e1884e39ba221f702b37778a2023-11-17T18:32:13ZengMDPI AGBrain Sciences2076-34252023-03-0113458010.3390/brainsci13040580Microanatomic Morphometric Characteristics of the Third Ventricle FloorMarios Theologou0Konstantinos Kouskouras1Konstantinos Natsis2Panagiotis Varoutis3Eleni Zaggelidou4Christos Tsonidis5Second Department of Neurosurgery, General Hospital of Thessaloniki Hippokratio, Aristotle University of Thessaloniki, 54642 Thessaloniki, GreeceDepartment of Radiology, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, GreeceDepartment of Anatomy and Surgical Anatomy, School of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, GreeceSecond Department of Neurosurgery, General Hospital of Thessaloniki Hippokratio, Aristotle University of Thessaloniki, 54642 Thessaloniki, GreeceForensic Medical Service of Thessaloniki, Ministry of Justice, 54634 Thessaloniki, GreeceSecond Department of Neurosurgery, General Hospital of Thessaloniki Hippokratio, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece<b>Background</b>: Endoscopic third ventriculostomy (ETV) is an effective treatment for hydrocephalus. The in-depth understanding of microanatomy is essential for accurate diagnosis, treatment and complications prevention. The aim of this study is to supplement the knowledge gap regarding the microanatomical metrics and correlations for which the literature includes only scarce mentions at best. <b>Methods:</b> This is a descriptive microanatomical study including 25 cadaver brains. Specimens from donors with neurological, psychiatric disorders or alcohol abuse were excluded. Surgical loops were used for harvesting. High-precision tools were employed to dissect and measure the anatomical landmarks under a surgical microscope. Each measurement was performed in three consecutive attempts and outliers were rejected. RStudio was used for statistical analysis. Distribution was evaluated employing the Shapiro–Wilk test. Normally distributed values were presented as mean and standard deviation, and others as median and interquartile range. <b>Results:</b> The age of the donors was 61.72 (±10.08) years. The distance from the anterior aspect of the foramen of Monro to the anterior margin of the mamillary body was 16.83 (±1.04) mm, and to the posterior margin was 16.76 (±1.9) mm. The distance from the anterior mamillary body margin to the infundibulum was 6.39 (±1.9) mm, to the optic recess was 8.25 (±1.84) mm, and to the apex of the vertebral artery was 5.05 (±1.62) mm. The distance from the anterior commissure to the brain aqueduct was 22.46 (±2.29) mm, and to the infundibulum was 13.93 (±2.54) mm. The mamillary body diameter was 4.91 (±0.34) mm in the anteroposterior and 4.21 (±0.48) mm in the cranio-caudal plane. The intraventricular segment was protruding by 1.63 (±0.46) mm. The diameter of the hypothalamus on the anterior margin of mamillary bodies was 1.37 (±0.75) mm, of the Liliequist membrane was 0.19 (±0.07) mm and of the lamina terminalis was 0.35 (±0.32) mm. <b>Conclusion:</b> The presented microanatomical measurements and correlations are expected to contribute to the improvement of ETV safety.https://www.mdpi.com/2076-3425/13/4/580endoscopic third ventriculostomymamillary bodyhypothalamusbasilar arteryLiliequist membranelamina terminalis |
| spellingShingle | Marios Theologou Konstantinos Kouskouras Konstantinos Natsis Panagiotis Varoutis Eleni Zaggelidou Christos Tsonidis Microanatomic Morphometric Characteristics of the Third Ventricle Floor Brain Sciences endoscopic third ventriculostomy mamillary body hypothalamus basilar artery Liliequist membrane lamina terminalis |
| title | Microanatomic Morphometric Characteristics of the Third Ventricle Floor |
| title_full | Microanatomic Morphometric Characteristics of the Third Ventricle Floor |
| title_fullStr | Microanatomic Morphometric Characteristics of the Third Ventricle Floor |
| title_full_unstemmed | Microanatomic Morphometric Characteristics of the Third Ventricle Floor |
| title_short | Microanatomic Morphometric Characteristics of the Third Ventricle Floor |
| title_sort | microanatomic morphometric characteristics of the third ventricle floor |
| topic | endoscopic third ventriculostomy mamillary body hypothalamus basilar artery Liliequist membrane lamina terminalis |
| url | https://www.mdpi.com/2076-3425/13/4/580 |
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