Rapid joule heating improves vitrification based cryopreservation

Lower concentrations of toxic cryoprotective agents require rapid and scalable rewarming techniques. Here, the authors report on a joule heating–based platform where samples are rapidly rewarmed by contact with a voltage pulsed electrical conductor and demonstrate the preservation of Drosophila embr...

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Dades bibliogràfiques
Autors principals: Li Zhan, Zonghu Han, Qi Shao, Michael L. Etheridge, Thomas Hays, John C. Bischof
Format: Article
Idioma:English
Publicat: Nature Portfolio 2022-10-01
Col·lecció:Nature Communications
Accés en línia:https://doi.org/10.1038/s41467-022-33546-9
Descripció
Sumari:Lower concentrations of toxic cryoprotective agents require rapid and scalable rewarming techniques. Here, the authors report on a joule heating–based platform where samples are rapidly rewarmed by contact with a voltage pulsed electrical conductor and demonstrate the preservation of Drosophila embryos and rat kidney slices.
ISSN:2041-1723