The Association between Nutrient Patterns and Polycystic Ovary Syndrome: A Case-Control Study
Polycystic ovary syndrome (PCOS) is a common endocrine abnormality among reproductive-aged women. This study aimed to investigate the relevance of major nutrient patterns and PCOS. Methods: This age-body mass index (BMI) matched case-control study was conducted among 216 women with and without PCOS....
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| Format: | Article |
| Language: | English |
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Shahid Sadoughi University of Medical Sciences and Health Services
2022-01-01
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| Series: | Journal of Nutrition and Food Security |
| Subjects: | |
| Online Access: | http://jnfs.ssu.ac.ir/article-1-392-en.html |
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| author | Asieh Panjeshahin Amin Salehi-Abargouei Akram Ghadiri-Anari Ahmadreza Rasouli Mahdieh Hosseinzadeh |
| author_facet | Asieh Panjeshahin Amin Salehi-Abargouei Akram Ghadiri-Anari Ahmadreza Rasouli Mahdieh Hosseinzadeh |
| author_sort | Asieh Panjeshahin |
| collection | DOAJ |
| description | Polycystic ovary syndrome (PCOS) is a common endocrine abnormality among reproductive-aged women. This study aimed to investigate the relevance of major nutrient patterns and PCOS. Methods: This age-body mass index (BMI) matched case-control study was conducted among 216 women with and without PCOS. The validated 178-items food frequency questionnaire (FFQ) was used for driving nutrient patterns. Logistic regression was used to assess the relationship between nutrient patterns and odds of PCOS. Results: Four major nutrient patterns were identified (65% of the variances of nutrient intake), including factor 1) high in carbohydrate, saturated fatty acids (SFA), total fat, and low in Eicosapentaenoic acid (EPA), Docosahexaenoic acid (DHA), factor 2) high loadings of SFA, cholesterol, vitamin D, total fat, and total fiber, factor 3) high in total fiber, EPA, DHA, chrome, vitamin C, vitamin D, and polyunsaturated fatty acids (PUFA), and factor 4) high loaded by fat, sodium, SFA, and low in vitamin D. Factor 1 and factor 4 nutrient patterns significantly increased the odds of PCOS (OR = 7.42; 95% CI 2.86, 18.1; Ptrend < 0.001) and (OR = 11.32; 95% CI 4.3, 29.97; Ptrend < 0.001), respectively. Also, the moderate adherence to factor 3 nutrient pattern had a protective effect on odds of PCOS (OR = 0.77; 95% CI 0.39, 0.98; Ptrend = 0.04). Conclusion: It was found that factor 1 nutrient pattern increased the odds of PCOS and factor 3 nutrient pattern decreased the risk of PCOS. More prospective studies are required to confirm the study findings. |
| first_indexed | 2024-04-11T17:52:27Z |
| format | Article |
| id | doaj.art-bb518949ac404a8e9472a4fe7483d069 |
| institution | Directory Open Access Journal |
| issn | 2476-7417 2476-7425 |
| language | English |
| last_indexed | 2024-04-11T17:52:27Z |
| publishDate | 2022-01-01 |
| publisher | Shahid Sadoughi University of Medical Sciences and Health Services |
| record_format | Article |
| series | Journal of Nutrition and Food Security |
| spelling | doaj.art-bb518949ac404a8e9472a4fe7483d0692022-12-22T04:11:03ZengShahid Sadoughi University of Medical Sciences and Health ServicesJournal of Nutrition and Food Security2476-74172476-74252022-01-01716987The Association between Nutrient Patterns and Polycystic Ovary Syndrome: A Case-Control StudyAsieh Panjeshahin0Amin Salehi-Abargouei1Akram Ghadiri-Anari2Ahmadreza Rasouli3Mahdieh Hosseinzadeh4 Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Department of Nutrition, School of Health, Qazvin University of Medical Sciences, Qazvin, Iran. Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Polycystic ovary syndrome (PCOS) is a common endocrine abnormality among reproductive-aged women. This study aimed to investigate the relevance of major nutrient patterns and PCOS. Methods: This age-body mass index (BMI) matched case-control study was conducted among 216 women with and without PCOS. The validated 178-items food frequency questionnaire (FFQ) was used for driving nutrient patterns. Logistic regression was used to assess the relationship between nutrient patterns and odds of PCOS. Results: Four major nutrient patterns were identified (65% of the variances of nutrient intake), including factor 1) high in carbohydrate, saturated fatty acids (SFA), total fat, and low in Eicosapentaenoic acid (EPA), Docosahexaenoic acid (DHA), factor 2) high loadings of SFA, cholesterol, vitamin D, total fat, and total fiber, factor 3) high in total fiber, EPA, DHA, chrome, vitamin C, vitamin D, and polyunsaturated fatty acids (PUFA), and factor 4) high loaded by fat, sodium, SFA, and low in vitamin D. Factor 1 and factor 4 nutrient patterns significantly increased the odds of PCOS (OR = 7.42; 95% CI 2.86, 18.1; Ptrend < 0.001) and (OR = 11.32; 95% CI 4.3, 29.97; Ptrend < 0.001), respectively. Also, the moderate adherence to factor 3 nutrient pattern had a protective effect on odds of PCOS (OR = 0.77; 95% CI 0.39, 0.98; Ptrend = 0.04). Conclusion: It was found that factor 1 nutrient pattern increased the odds of PCOS and factor 3 nutrient pattern decreased the risk of PCOS. More prospective studies are required to confirm the study findings.http://jnfs.ssu.ac.ir/article-1-392-en.htmlnutrient patternpolycystic ovary syndromefactor analysisdiet |
| spellingShingle | Asieh Panjeshahin Amin Salehi-Abargouei Akram Ghadiri-Anari Ahmadreza Rasouli Mahdieh Hosseinzadeh The Association between Nutrient Patterns and Polycystic Ovary Syndrome: A Case-Control Study Journal of Nutrition and Food Security nutrient pattern polycystic ovary syndrome factor analysis diet |
| title | The Association between Nutrient Patterns and Polycystic Ovary Syndrome: A Case-Control Study |
| title_full | The Association between Nutrient Patterns and Polycystic Ovary Syndrome: A Case-Control Study |
| title_fullStr | The Association between Nutrient Patterns and Polycystic Ovary Syndrome: A Case-Control Study |
| title_full_unstemmed | The Association between Nutrient Patterns and Polycystic Ovary Syndrome: A Case-Control Study |
| title_short | The Association between Nutrient Patterns and Polycystic Ovary Syndrome: A Case-Control Study |
| title_sort | association between nutrient patterns and polycystic ovary syndrome a case control study |
| topic | nutrient pattern polycystic ovary syndrome factor analysis diet |
| url | http://jnfs.ssu.ac.ir/article-1-392-en.html |
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