Using the avian mutant talpid2 as a disease model for understanding the oral-facial phenotypes of oral-facial-digital syndrome

Using the avian mutant talpid2 as a disease model for understanding the oral-facial phenotypes of oral-facial-digital syndrome

Oral-facial-digital syndrome (OFD) is a ciliopathy that is characterized by oral-facial abnormalities, including cleft lip and/or palate, broad nasal root, dental anomalies, micrognathia and glossal defects. In addition, these individuals have several other characteristic abnormalities that are typi...

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Bibliographic Details
Main Authors: Elizabeth N. Schock, Ching-Fang Chang, Jaime N. Struve, Ya-Ting Chang, Julie Chang, Mary E. Delany, Samantha A. Brugmann
Format: Article
Language:English
Published: The Company of Biologists 2015-08-01
Series:Disease Models & Mechanisms
Subjects:
Primary cilia
Craniofacial
Neural crest
talpid2
Ciliopathies
Chicken
Oral-facial-digital syndrome
Online Access:http://dmm.biologists.org/content/8/8/855

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