Genetic and environment effects on structural neuroimaging endophenotype for bipolar disorder: a novel molecular approach
Abstract We investigated gene–environment effects on structural brain endophenotype in bipolar disorder (BD) using a novel method of combining polygenic risk scores with epigenetic signatures since traditional methods of examining the family history and trauma effects have significant limitations. T...
Main Authors: | Bo Hu, Jungwon Cha, Janice M. Fullerton, Sonia Hesam-Shariati, Kunio Nakamura, John I. Nurnberger, Amit Anand |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-04-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-022-01892-3 |
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