Ambient Air Pollution and Risk for Stroke Hospitalization: Impact on Susceptible Groups
Stroke is a leading cause of death, and air pollution is associated with stroke hospitalization. However, the susceptibility factors are unclear. Retrospective studies from 2014 to 2018 in Kaohsiung, Taiwan, were analyzed. Adult patients (>17 years) admitted to a medical center with stroke diagno...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Toxics |
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| Online Access: | https://www.mdpi.com/2305-6304/10/7/350 |
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| author | Chia-Hau Chang Shih-Hsuan Chen Peng-Huei Liu Kuo-Chen Huang I-Min Chiu Hsiu-Yung Pan Fu-Jen Cheng |
| author_facet | Chia-Hau Chang Shih-Hsuan Chen Peng-Huei Liu Kuo-Chen Huang I-Min Chiu Hsiu-Yung Pan Fu-Jen Cheng |
| author_sort | Chia-Hau Chang |
| collection | DOAJ |
| description | Stroke is a leading cause of death, and air pollution is associated with stroke hospitalization. However, the susceptibility factors are unclear. Retrospective studies from 2014 to 2018 in Kaohsiung, Taiwan, were analyzed. Adult patients (>17 years) admitted to a medical center with stroke diagnosis were enrolled and patient characteristics and comorbidities were recorded. Air pollutant measurements, including those of particulate matter (PM) with aerodynamic diameters < 10 μm (PM<sub>10</sub>) and < 2.5 μm (PM<sub>2.5</sub>), nitrogen dioxide (NO<sub>2</sub>), and ozone (O<sub>3</sub>), were collected from air quality monitoring stations. During the study period, interquartile range (IQR) increments in PM<sub>2.5</sub> on lag3 and lag4 were 12.3% (95% CI, 1.1–24.7%) and 11.5% (95% CI, 0.3–23.9%) concerning the risk of stroke hospitalization, respectively. Subgroup analysis revealed that the risk of stroke hospitalization after exposure to PM<sub>2.5</sub> was greater for those with advanced age (≥80 years, interaction <i>p</i> = 0.045) and hypertension (interaction <i>p</i> = 0.034), after adjusting for temperature and humidity. A dose-dependent effect of PM<sub>2.5</sub> on stroke hospitalization was evident. This is one of few studies focusing on the health effects of PM<sub>2.5</sub> for patients with risk factors of stroke. We found that patients with risk factors, such as advanced age and hypertension, are more susceptible to PM<sub>2.5</sub> impacts on stroke hospitalization. |
| first_indexed | 2024-03-09T05:47:26Z |
| format | Article |
| id | doaj.art-bb56d157699040cba11c503986858f86 |
| institution | Directory Open Access Journal |
| issn | 2305-6304 |
| language | English |
| last_indexed | 2024-03-09T05:47:26Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxics |
| spelling | doaj.art-bb56d157699040cba11c503986858f862023-12-03T12:20:29ZengMDPI AGToxics2305-63042022-06-0110735010.3390/toxics10070350Ambient Air Pollution and Risk for Stroke Hospitalization: Impact on Susceptible GroupsChia-Hau Chang0Shih-Hsuan Chen1Peng-Huei Liu2Kuo-Chen Huang3I-Min Chiu4Hsiu-Yung Pan5Fu-Jen Cheng6Department of Emergency Medicine, New Taipei Municipal Tucheng Hospital, New Taipei 236, TaiwanDepartment of Neurology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City 83301, TaiwanDepartment of Emergency Medicine, Chang Gung Memorial Hospital, Taoyuan 333, TaiwanCollege of Medicine, Chang Gung University, Guishan District, Taoyuan City 333, TaiwanCollege of Medicine, Chang Gung University, Guishan District, Taoyuan City 333, TaiwanCollege of Medicine, Chang Gung University, Guishan District, Taoyuan City 333, TaiwanCollege of Medicine, Chang Gung University, Guishan District, Taoyuan City 333, TaiwanStroke is a leading cause of death, and air pollution is associated with stroke hospitalization. However, the susceptibility factors are unclear. Retrospective studies from 2014 to 2018 in Kaohsiung, Taiwan, were analyzed. Adult patients (>17 years) admitted to a medical center with stroke diagnosis were enrolled and patient characteristics and comorbidities were recorded. Air pollutant measurements, including those of particulate matter (PM) with aerodynamic diameters < 10 μm (PM<sub>10</sub>) and < 2.5 μm (PM<sub>2.5</sub>), nitrogen dioxide (NO<sub>2</sub>), and ozone (O<sub>3</sub>), were collected from air quality monitoring stations. During the study period, interquartile range (IQR) increments in PM<sub>2.5</sub> on lag3 and lag4 were 12.3% (95% CI, 1.1–24.7%) and 11.5% (95% CI, 0.3–23.9%) concerning the risk of stroke hospitalization, respectively. Subgroup analysis revealed that the risk of stroke hospitalization after exposure to PM<sub>2.5</sub> was greater for those with advanced age (≥80 years, interaction <i>p</i> = 0.045) and hypertension (interaction <i>p</i> = 0.034), after adjusting for temperature and humidity. A dose-dependent effect of PM<sub>2.5</sub> on stroke hospitalization was evident. This is one of few studies focusing on the health effects of PM<sub>2.5</sub> for patients with risk factors of stroke. We found that patients with risk factors, such as advanced age and hypertension, are more susceptible to PM<sub>2.5</sub> impacts on stroke hospitalization.https://www.mdpi.com/2305-6304/10/7/350particulate matterair pollutionstrokehospitalizationsusceptible groupPM<sub>2.5</sub> |
| spellingShingle | Chia-Hau Chang Shih-Hsuan Chen Peng-Huei Liu Kuo-Chen Huang I-Min Chiu Hsiu-Yung Pan Fu-Jen Cheng Ambient Air Pollution and Risk for Stroke Hospitalization: Impact on Susceptible Groups Toxics particulate matter air pollution stroke hospitalization susceptible group PM<sub>2.5</sub> |
| title | Ambient Air Pollution and Risk for Stroke Hospitalization: Impact on Susceptible Groups |
| title_full | Ambient Air Pollution and Risk for Stroke Hospitalization: Impact on Susceptible Groups |
| title_fullStr | Ambient Air Pollution and Risk for Stroke Hospitalization: Impact on Susceptible Groups |
| title_full_unstemmed | Ambient Air Pollution and Risk for Stroke Hospitalization: Impact on Susceptible Groups |
| title_short | Ambient Air Pollution and Risk for Stroke Hospitalization: Impact on Susceptible Groups |
| title_sort | ambient air pollution and risk for stroke hospitalization impact on susceptible groups |
| topic | particulate matter air pollution stroke hospitalization susceptible group PM<sub>2.5</sub> |
| url | https://www.mdpi.com/2305-6304/10/7/350 |
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