Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities
Saeideh Ebrahimiasl,1,2 Azmi Zakaria,3 Anuar Kassim,4 Sri Norleha Basri4 1Department of Nanotechnology, Institute of Advanced Technology, Universiti Putra Malaysia, Serdang, Malaysia; 2Department of Chemistry, Ahar Branch, Islamic Azad University, Ahar, Iran; 3Department of Physics, Universiti Putr...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2014-12-01
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| Series: | International Journal of Nanomedicine |
| Online Access: | http://www.dovepress.com/novel-conductive-polypyrrolezinc-oxidechitosan-bionanocomposite-synthe-peer-reviewed-article-IJN |
| _version_ | 1819291967698239488 |
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| author | Ebrahimiasl S Zakaria A Kassim A Basri SN |
| author_facet | Ebrahimiasl S Zakaria A Kassim A Basri SN |
| author_sort | Ebrahimiasl S |
| collection | DOAJ |
| description | Saeideh Ebrahimiasl,1,2 Azmi Zakaria,3 Anuar Kassim,4 Sri Norleha Basri4 1Department of Nanotechnology, Institute of Advanced Technology, Universiti Putra Malaysia, Serdang, Malaysia; 2Department of Chemistry, Ahar Branch, Islamic Azad University, Ahar, Iran; 3Department of Physics, Universiti Putra Malaysia, Serdang, Malaysia; 4Department of Chemistry, Universiti Putra Malaysia, Serdang, Malaysia Abstract: An antibacterial and conductive bionanocomposite (BNC) film consisting of polypyrrole (Ppy), zinc oxide (ZnO) nanoparticles (NPs), and chitosan (CS) was electrochemically synthesized on indium tin oxide (ITO) glass substrate by electrooxidation of 0.1 M pyrrole in aqueous solution containing appropriate amounts of ZnO NPs uniformly dispersed in CS. This method enables the room temperature electrosynthesis of BNC film consisting of ZnO NPs incorporated within the growing Ppy/CS composite. The morphology of Ppy/ZnO/CS BNC was characterized by scanning electron microscopy. ITO–Ppy/CS and ITO–Ppy/ZnO/CS bioelectrodes were characterized using the Fourier transform infrared technique, X-ray diffraction, and thermogravimetric analysis. The electrical conductivity of nanocomposites was investigated by a four-probe method. The prepared nanocomposites were analyzed for antioxidant activity using the 2,2-diphenyl-1-picrylhydrazyl assay. The results demonstrated that the antioxidant activity of nanocomposites increased remarkably by addition of ZnO NPs. The electrical conductivity of films showed a sudden decrease for lower weight ratios of ZnO NPs (5 wt%), while it was increased gradually for higher ratios (10, 15, and 20 wt%). The nanocomposites were analyzed for antibacterial activity against Gram-positive and Gram-negative bacteria. The results indicated that the synthesized BNC is effective against all of the studied bacteria, and its effectiveness is higher for Pseudomonas aeruginosa. The thermal stability and physical properties of BNC films were increased by an increase in the weight ratio of ZnO NPs, promising novel applications for the electrically conductive polysaccharide-based nanocomposites, particularly those that may exploit the antimicrobial nature of Ppy/ZnO/CS BNCs. Keywords: bionanocomposite, electrodeposition, conductive, antibacterial, antioxidant |
| first_indexed | 2024-12-24T03:47:03Z |
| format | Article |
| id | doaj.art-bb56ef24ff6e4b068454d0b6f24d6131 |
| institution | Directory Open Access Journal |
| issn | 1178-2013 |
| language | English |
| last_indexed | 2024-12-24T03:47:03Z |
| publishDate | 2014-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of Nanomedicine |
| spelling | doaj.art-bb56ef24ff6e4b068454d0b6f24d61312022-12-21T17:16:41ZengDove Medical PressInternational Journal of Nanomedicine1178-20132014-12-012015default21722719770Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activitiesEbrahimiasl SZakaria AKassim ABasri SNSaeideh Ebrahimiasl,1,2 Azmi Zakaria,3 Anuar Kassim,4 Sri Norleha Basri4 1Department of Nanotechnology, Institute of Advanced Technology, Universiti Putra Malaysia, Serdang, Malaysia; 2Department of Chemistry, Ahar Branch, Islamic Azad University, Ahar, Iran; 3Department of Physics, Universiti Putra Malaysia, Serdang, Malaysia; 4Department of Chemistry, Universiti Putra Malaysia, Serdang, Malaysia Abstract: An antibacterial and conductive bionanocomposite (BNC) film consisting of polypyrrole (Ppy), zinc oxide (ZnO) nanoparticles (NPs), and chitosan (CS) was electrochemically synthesized on indium tin oxide (ITO) glass substrate by electrooxidation of 0.1 M pyrrole in aqueous solution containing appropriate amounts of ZnO NPs uniformly dispersed in CS. This method enables the room temperature electrosynthesis of BNC film consisting of ZnO NPs incorporated within the growing Ppy/CS composite. The morphology of Ppy/ZnO/CS BNC was characterized by scanning electron microscopy. ITO–Ppy/CS and ITO–Ppy/ZnO/CS bioelectrodes were characterized using the Fourier transform infrared technique, X-ray diffraction, and thermogravimetric analysis. The electrical conductivity of nanocomposites was investigated by a four-probe method. The prepared nanocomposites were analyzed for antioxidant activity using the 2,2-diphenyl-1-picrylhydrazyl assay. The results demonstrated that the antioxidant activity of nanocomposites increased remarkably by addition of ZnO NPs. The electrical conductivity of films showed a sudden decrease for lower weight ratios of ZnO NPs (5 wt%), while it was increased gradually for higher ratios (10, 15, and 20 wt%). The nanocomposites were analyzed for antibacterial activity against Gram-positive and Gram-negative bacteria. The results indicated that the synthesized BNC is effective against all of the studied bacteria, and its effectiveness is higher for Pseudomonas aeruginosa. The thermal stability and physical properties of BNC films were increased by an increase in the weight ratio of ZnO NPs, promising novel applications for the electrically conductive polysaccharide-based nanocomposites, particularly those that may exploit the antimicrobial nature of Ppy/ZnO/CS BNCs. Keywords: bionanocomposite, electrodeposition, conductive, antibacterial, antioxidanthttp://www.dovepress.com/novel-conductive-polypyrrolezinc-oxidechitosan-bionanocomposite-synthe-peer-reviewed-article-IJN |
| spellingShingle | Ebrahimiasl S Zakaria A Kassim A Basri SN Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities International Journal of Nanomedicine |
| title | Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities |
| title_full | Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities |
| title_fullStr | Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities |
| title_full_unstemmed | Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities |
| title_short | Novel conductive polypyrrole/zinc oxide/chitosan bionanocomposite: synthesis, characterization, antioxidant, and antibacterial activities |
| title_sort | novel conductive polypyrrole zinc oxide chitosan bionanocomposite synthesis characterization antioxidant and antibacterial activities |
| url | http://www.dovepress.com/novel-conductive-polypyrrolezinc-oxidechitosan-bionanocomposite-synthe-peer-reviewed-article-IJN |
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