Paragonimiasis in tuberculosis patients in Nagaland, India
Background: One of the infections that mimic tuberculosis (TB) is paragonimiasis (PRG), a foodborne parasitic disease caused by lung flukes of the genus Paragonimus. In the northeastern states of India, TB and PRG are endemic; however, PRG is rarely included in the differential diagnosis of TB. Obje...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2016-09-01
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| Series: | Global Health Action |
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| Online Access: | http://www.globalhealthaction.net/index.php/gha/article/view/32387/pdf_300 |
| _version_ | 1819238672205086720 |
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| author | Mrinalini Das Katerina Doleckova Rahul Shenoy Jagadish Mahanta Kanwar Narain K. Rekha Devi Tongmeth Konyak Homa Mansoor Petros Isaakidis |
| author_facet | Mrinalini Das Katerina Doleckova Rahul Shenoy Jagadish Mahanta Kanwar Narain K. Rekha Devi Tongmeth Konyak Homa Mansoor Petros Isaakidis |
| author_sort | Mrinalini Das |
| collection | DOAJ |
| description | Background: One of the infections that mimic tuberculosis (TB) is paragonimiasis (PRG), a foodborne parasitic disease caused by lung flukes of the genus Paragonimus. In the northeastern states of India, TB and PRG are endemic; however, PRG is rarely included in the differential diagnosis of TB. Objective: To address limited evidence on the dual burden of TB and PRG in northeastern India, we aimed to document the prevalence of PRG among TB patients using sputum smear, stool examination for children <15 years and ELISA. Design: A cross-sectional study of patients receiving TB treatment in the Médecins Sans Frontières (MSF)-supported TB programme in Mon district, in collaboration with the Regional Medical Research Centre (RMRC), Dibrugarh, Assam, between November 2012 and December 2013. Results: Of 96 patients screened between November 2012 and December 2013, three (3%) had pulmonary PRG and were successfully treated with praziquantel. Conclusions: PRG should be considered in the TB diagnostic algorithms in PRG–TB dual burden areas. In case of TB–PRG co-infection, it is preferable to treat PRG first followed by anti-TB treatment a few days later. |
| first_indexed | 2024-12-23T13:39:57Z |
| format | Article |
| id | doaj.art-bb5e705ae0d443a692175e188bf9bd15 |
| institution | Directory Open Access Journal |
| issn | 1654-9880 |
| language | English |
| last_indexed | 2024-12-23T13:39:57Z |
| publishDate | 2016-09-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Global Health Action |
| spelling | doaj.art-bb5e705ae0d443a692175e188bf9bd152022-12-21T17:44:54ZengTaylor & Francis GroupGlobal Health Action1654-98802016-09-01901410.3402/gha.v9.3238732387Paragonimiasis in tuberculosis patients in Nagaland, IndiaMrinalini Das0Katerina Doleckova1Rahul Shenoy2Jagadish Mahanta3Kanwar Narain4K. Rekha Devi5Tongmeth Konyak6Homa Mansoor7Petros Isaakidis8 Médecins Sans Frontières (MSF), Delhi, India Médecins Sans Frontières (MSF), Mon, Nagaland, India Médecins Sans Frontières (MSF), Mon, Nagaland, India Regional Medical Research Centre (RMRC), Dibrugarh, Assam, India Regional Medical Research Centre (RMRC), Dibrugarh, Assam, India Regional Medical Research Centre (RMRC), Dibrugarh, Assam, India Médecins Sans Frontières (MSF), Mon, Nagaland, India Médecins Sans Frontières (MSF), Delhi, India Médecins Sans Frontières (MSF), Delhi, IndiaBackground: One of the infections that mimic tuberculosis (TB) is paragonimiasis (PRG), a foodborne parasitic disease caused by lung flukes of the genus Paragonimus. In the northeastern states of India, TB and PRG are endemic; however, PRG is rarely included in the differential diagnosis of TB. Objective: To address limited evidence on the dual burden of TB and PRG in northeastern India, we aimed to document the prevalence of PRG among TB patients using sputum smear, stool examination for children <15 years and ELISA. Design: A cross-sectional study of patients receiving TB treatment in the Médecins Sans Frontières (MSF)-supported TB programme in Mon district, in collaboration with the Regional Medical Research Centre (RMRC), Dibrugarh, Assam, between November 2012 and December 2013. Results: Of 96 patients screened between November 2012 and December 2013, three (3%) had pulmonary PRG and were successfully treated with praziquantel. Conclusions: PRG should be considered in the TB diagnostic algorithms in PRG–TB dual burden areas. In case of TB–PRG co-infection, it is preferable to treat PRG first followed by anti-TB treatment a few days later.http://www.globalhealthaction.net/index.php/gha/article/view/32387/pdf_300lung flukenortheastzoonotic infectionpraziquanteloperational research |
| spellingShingle | Mrinalini Das Katerina Doleckova Rahul Shenoy Jagadish Mahanta Kanwar Narain K. Rekha Devi Tongmeth Konyak Homa Mansoor Petros Isaakidis Paragonimiasis in tuberculosis patients in Nagaland, India Global Health Action lung fluke northeast zoonotic infection praziquantel operational research |
| title | Paragonimiasis in tuberculosis patients in Nagaland, India |
| title_full | Paragonimiasis in tuberculosis patients in Nagaland, India |
| title_fullStr | Paragonimiasis in tuberculosis patients in Nagaland, India |
| title_full_unstemmed | Paragonimiasis in tuberculosis patients in Nagaland, India |
| title_short | Paragonimiasis in tuberculosis patients in Nagaland, India |
| title_sort | paragonimiasis in tuberculosis patients in nagaland india |
| topic | lung fluke northeast zoonotic infection praziquantel operational research |
| url | http://www.globalhealthaction.net/index.php/gha/article/view/32387/pdf_300 |
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