Enrichment of type I interferon signaling in colonic group 2 innate lymphoid cells in experimental colitis

Enrichment of type I interferon signaling in colonic group 2 innate lymphoid cells in experimental colitis

Group 2 innate lymphoid cells (ILC2s) serve as frontline defenses against parasites. However, excluding helminth infections, it is poorly understood how ILC2s function in intestinal inflammation, including inflammatory bowel disease. Here, we analyzed the global gene expression of ILC2s in healthy a...

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Main Authors: Emi Irie, Rino Ishihara, Ichiro Mizushima, Shunya Hatai, Yuya Hagihara, Yoshiaki Takada, Junya Tsunoda, Kentaro Iwata, Yuta Matsubara, Yusuke Yoshimatsu, Hiroki Kiyohara, Nobuhito Taniki, Tomohisa Sujino, Kaoru Takabayashi, Naoki Hosoe, Haruhiko Ogata, Toshiaki Teratani, Nobuhiro Nakamoto, Yohei Mikami, Takanori Kanai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
ILC2 - group 2 innate lymphoid cell
type I interferon
ifnar
colitis
ibd
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.982827/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.982827/full

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