The synthesis diagnostic test systems on the basis of polymer microspheres in the presence of polyvinylpyrrolidone modified with an amino acid
Styrene-divinylbenzene particles (6 microns in diameter) with carboxyl groups on the surface have been synthesized by seed polymerization in the presence of an organosilicon carboxyl-containing surfactant soluble in the monomer phase. It has been shown that carboxyl groups on the microsphere surface...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | Russian |
Published: |
MIREA - Russian Technological University
2010-06-01
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Series: | Тонкие химические технологии |
Subjects: | |
Online Access: | https://www.finechem-mirea.ru/jour/article/view/980 |
Summary: | Styrene-divinylbenzene particles (6 microns in diameter) with carboxyl groups on the surface have been synthesized by seed polymerization in the presence of an organosilicon carboxyl-containing surfactant soluble in the monomer phase. It has been shown that carboxyl groups on the microsphere surface are accessible for covalent immobilization of bioligands and alanine-modified polyvinylpyrrolidone. It was supposed that applying modified polyvinylpyrrolidone for obtaining diagnostic systems based on polymer microspheres is very perspective. |
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ISSN: | 2410-6593 2686-7575 |