The synthesis diagnostic test systems on the basis of polymer microspheres in the presence of polyvinylpyrrolidone modified with an amino acid
Styrene-divinylbenzene particles (6 microns in diameter) with carboxyl groups on the surface have been synthesized by seed polymerization in the presence of an organosilicon carboxyl-containing surfactant soluble in the monomer phase. It has been shown that carboxyl groups on the microsphere surface...
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| Format: | Article |
| Language: | Russian |
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MIREA - Russian Technological University
2010-06-01
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| Series: | Тонкие химические технологии |
| Subjects: | |
| Online Access: | https://www.finechem-mirea.ru/jour/article/view/980 |
| _version_ | 1797882201530957824 |
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| author | Z. B. Artykova I. A. Gritskova S. A. Gusev L. Y. Basyreva V. A. Sotchilin M. I. Shtilman A. V. Goryachaya G. P. Kheynman S. A. Kedik N. I. Prokopov |
| author_facet | Z. B. Artykova I. A. Gritskova S. A. Gusev L. Y. Basyreva V. A. Sotchilin M. I. Shtilman A. V. Goryachaya G. P. Kheynman S. A. Kedik N. I. Prokopov |
| author_sort | Z. B. Artykova |
| collection | DOAJ |
| description | Styrene-divinylbenzene particles (6 microns in diameter) with carboxyl groups on the surface have been synthesized by seed polymerization in the presence of an organosilicon carboxyl-containing surfactant soluble in the monomer phase. It has been shown that carboxyl groups on the microsphere surface are accessible for covalent immobilization of bioligands and alanine-modified polyvinylpyrrolidone. It was supposed that applying modified polyvinylpyrrolidone for obtaining diagnostic systems based on polymer microspheres is very perspective. |
| first_indexed | 2024-04-10T03:31:11Z |
| format | Article |
| id | doaj.art-bb629cf8c8f045318044f7d8ba733a25 |
| institution | Directory Open Access Journal |
| issn | 2410-6593 2686-7575 |
| language | Russian |
| last_indexed | 2024-04-10T03:31:11Z |
| publishDate | 2010-06-01 |
| publisher | MIREA - Russian Technological University |
| record_format | Article |
| series | Тонкие химические технологии |
| spelling | doaj.art-bb629cf8c8f045318044f7d8ba733a252023-03-13T07:25:31ZrusMIREA - Russian Technological UniversityТонкие химические технологии2410-65932686-75752010-06-01538287974The synthesis diagnostic test systems on the basis of polymer microspheres in the presence of polyvinylpyrrolidone modified with an amino acidZ. B. Artykova0I. A. Gritskova1S. A. Gusev2L. Y. Basyreva3V. A. Sotchilin4M. I. Shtilman5A. V. Goryachaya6G. P. Kheynman7S. A. Kedik8N. I. Prokopov9M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571ФГУ «Научно-исследовательский институт физико-химической медицины» Федерального медико-биологического агенства РоссииФГУ «Научно-исследовательский институт физико-химической медицины» Федерального медико-биологического агенства РоссииАНО «Синтез полимерных сорбентов»РФХТУ им.Д.И.МенделееваРФХТУ им.Д.И.МенделееваM.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571Styrene-divinylbenzene particles (6 microns in diameter) with carboxyl groups on the surface have been synthesized by seed polymerization in the presence of an organosilicon carboxyl-containing surfactant soluble in the monomer phase. It has been shown that carboxyl groups on the microsphere surface are accessible for covalent immobilization of bioligands and alanine-modified polyvinylpyrrolidone. It was supposed that applying modified polyvinylpyrrolidone for obtaining diagnostic systems based on polymer microspheres is very perspective.https://www.finechem-mirea.ru/jour/article/view/980organosilicon surfactant containing carboxyl groupspolymer microspherespolyvinylpyrrolidone modified with amino acid |
| spellingShingle | Z. B. Artykova I. A. Gritskova S. A. Gusev L. Y. Basyreva V. A. Sotchilin M. I. Shtilman A. V. Goryachaya G. P. Kheynman S. A. Kedik N. I. Prokopov The synthesis diagnostic test systems on the basis of polymer microspheres in the presence of polyvinylpyrrolidone modified with an amino acid Тонкие химические технологии organosilicon surfactant containing carboxyl groups polymer microspheres polyvinylpyrrolidone modified with amino acid |
| title | The synthesis diagnostic test systems on the basis of polymer microspheres in the presence of polyvinylpyrrolidone modified with an amino acid |
| title_full | The synthesis diagnostic test systems on the basis of polymer microspheres in the presence of polyvinylpyrrolidone modified with an amino acid |
| title_fullStr | The synthesis diagnostic test systems on the basis of polymer microspheres in the presence of polyvinylpyrrolidone modified with an amino acid |
| title_full_unstemmed | The synthesis diagnostic test systems on the basis of polymer microspheres in the presence of polyvinylpyrrolidone modified with an amino acid |
| title_short | The synthesis diagnostic test systems on the basis of polymer microspheres in the presence of polyvinylpyrrolidone modified with an amino acid |
| title_sort | synthesis diagnostic test systems on the basis of polymer microspheres in the presence of polyvinylpyrrolidone modified with an amino acid |
| topic | organosilicon surfactant containing carboxyl groups polymer microspheres polyvinylpyrrolidone modified with amino acid |
| url | https://www.finechem-mirea.ru/jour/article/view/980 |
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