Original enzyme-catalyzed synthesis of chalcones: Utilization of hydrolase promiscuity
E-chalcone was obtained with very high stereoselectivity for the first time by an enzyme-catalyzed Claisen-Schmidt condensation between benzaldehyde and acetophenone. From a set of lipases, only that from hog pancreas demonstrated promiscuity, catalyzing the reaction in the presence of imid...
Main Authors: | Mitrev Yavor N., Mehandzhiyski Aleksander Y., Batovska Daniela I., Liese Andreas, Galunsky Boris |
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Format: | Article |
Language: | English |
Published: |
Serbian Chemical Society
2016-01-01
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Series: | Journal of the Serbian Chemical Society |
Subjects: | |
Online Access: | http://www.doiserbia.nb.rs/img/doi/0352-5139/2016/0352-51391600069M.pdf |
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