Age-standardized mortality rates related to viral hepatitis in Brazil
Abstract Background Liver-related mortality has been increasing worldwide. We aimed to estimate the age-standardized mortality rates from viral hepatitis in Brazil. Methods The Brazilian National Death Registry was analyzed from 2008 to 2014. Viral hepatitis deaths were defined by the following ICD-...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-07-01
|
| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12879-017-2619-y |
| _version_ | 1819114922885251072 |
|---|---|
| author | Hugo Perazzo Antonio G Pacheco Paula M Luz Rodolfo Castro Chris Hyde Juliana Fittipaldi Caroline Rigolon Sandra W Cardoso Beatriz Grinsztejn Valdiléa G Veloso |
| author_facet | Hugo Perazzo Antonio G Pacheco Paula M Luz Rodolfo Castro Chris Hyde Juliana Fittipaldi Caroline Rigolon Sandra W Cardoso Beatriz Grinsztejn Valdiléa G Veloso |
| author_sort | Hugo Perazzo |
| collection | DOAJ |
| description | Abstract Background Liver-related mortality has been increasing worldwide. We aimed to estimate the age-standardized mortality rates from viral hepatitis in Brazil. Methods The Brazilian National Death Registry was analyzed from 2008 to 2014. Viral hepatitis deaths were defined by the following ICD-10 codes in the death certificate: hepatitis A [B15.0; B15.9]; hepatitis B [B16.2; B16.9; B18.1]; hepatitis C [B17.1; B18.2]; hepatitis Delta [B16.0; B16.1; B18.0; B17.0] and other viral hepatitis [B17.2; B17.8; B18.8; B18.9; B19.0; B19.9]. Crude mortality rates were calculated by the ratio between total number of deaths and estimated population. Mortality rates were age-standardized by the direct method using the WHO standard population. Results Thirty four thousand ,nine hundred seventy eight deaths had viral hepatitis mentioned in their death certificate [65% male, aged 58 years, 73% associated with hepatitis C]. Age-standardized mortality rate (95% CI) due to viral hepatitis was 2.695 (2.667–2.724) deaths per 100,000 inhabitants: South region had the higher rates [3.997 (3.911–4.085)]. Mortality rates associated with hepatitis A and Delta were 0.032 (0.029–0.035) and 0.028 (0.025–0.031), respectively. Hepatitis C mortality rates were 4-fold higher than those associated with hepatitis B [1.964 (1.940–1.989) vs 0.500 (0.488–0.512)]. South region had the higher rates for hepatitis C [3.163 (3.087–3.241)] and North had the higher rates for hepatitis A [0.066 (0.049–0.087)], B [0.986 (0.918–1.058)] and Delta [0.220 (0.190–0.253)]. Conclusion Viral hepatitis remains a major public health issue in Brazil. Mortality rates were not homogeneous across the country, suggesting that health policies should be customized according to geographical location. |
| first_indexed | 2024-12-22T04:53:00Z |
| format | Article |
| id | doaj.art-bb70336071f94c7cb567962be414eac3 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-22T04:53:00Z |
| publishDate | 2017-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-bb70336071f94c7cb567962be414eac32022-12-21T18:38:26ZengBMCBMC Infectious Diseases1471-23342017-07-0117111010.1186/s12879-017-2619-yAge-standardized mortality rates related to viral hepatitis in BrazilHugo Perazzo0Antonio G Pacheco1Paula M Luz2Rodolfo Castro3Chris Hyde4Juliana Fittipaldi5Caroline Rigolon6Sandra W Cardoso7Beatriz Grinsztejn8Valdiléa G Veloso9Fundação Oswaldo Cruz (FIOCRUZ), Instituto Nacional de Infectologia Evandro Chagas (INI), Laboratório de Pesquisa Clínica em DST e AIDS (LAPCLIN-AIDS)Fundação Oswaldo Cruz (FIOCRUZ), Programa de Computação Científica (PROCC)Fundação Oswaldo Cruz (FIOCRUZ), Instituto Nacional de Infectologia Evandro Chagas (INI), Laboratório de Pesquisa Clínica em DST e AIDS (LAPCLIN-AIDS)Fundação Oswaldo Cruz (FIOCRUZ), Instituto Nacional de Infectologia Evandro Chagas (INI), Laboratório de Pesquisa Clínica em DST e AIDS (LAPCLIN-AIDS)Institute of Health Research, Peninsula Technology Assessment Group (PenTAG), Evidence Synthesis and Modelling for Health Improvement (ESMI), University of Exeter Medical School, University of ExeterFundação Oswaldo Cruz (FIOCRUZ), Instituto Nacional de Infectologia Evandro Chagas (INI), Laboratório de Pesquisa Clínica em DST e AIDS (LAPCLIN-AIDS)Fundação Oswaldo Cruz (FIOCRUZ), Instituto Nacional de Infectologia Evandro Chagas (INI), Laboratório de Pesquisa Clínica em DST e AIDS (LAPCLIN-AIDS)Fundação Oswaldo Cruz (FIOCRUZ), Instituto Nacional de Infectologia Evandro Chagas (INI), Laboratório de Pesquisa Clínica em DST e AIDS (LAPCLIN-AIDS)Fundação Oswaldo Cruz (FIOCRUZ), Instituto Nacional de Infectologia Evandro Chagas (INI), Laboratório de Pesquisa Clínica em DST e AIDS (LAPCLIN-AIDS)Fundação Oswaldo Cruz (FIOCRUZ), Instituto Nacional de Infectologia Evandro Chagas (INI), Laboratório de Pesquisa Clínica em DST e AIDS (LAPCLIN-AIDS)Abstract Background Liver-related mortality has been increasing worldwide. We aimed to estimate the age-standardized mortality rates from viral hepatitis in Brazil. Methods The Brazilian National Death Registry was analyzed from 2008 to 2014. Viral hepatitis deaths were defined by the following ICD-10 codes in the death certificate: hepatitis A [B15.0; B15.9]; hepatitis B [B16.2; B16.9; B18.1]; hepatitis C [B17.1; B18.2]; hepatitis Delta [B16.0; B16.1; B18.0; B17.0] and other viral hepatitis [B17.2; B17.8; B18.8; B18.9; B19.0; B19.9]. Crude mortality rates were calculated by the ratio between total number of deaths and estimated population. Mortality rates were age-standardized by the direct method using the WHO standard population. Results Thirty four thousand ,nine hundred seventy eight deaths had viral hepatitis mentioned in their death certificate [65% male, aged 58 years, 73% associated with hepatitis C]. Age-standardized mortality rate (95% CI) due to viral hepatitis was 2.695 (2.667–2.724) deaths per 100,000 inhabitants: South region had the higher rates [3.997 (3.911–4.085)]. Mortality rates associated with hepatitis A and Delta were 0.032 (0.029–0.035) and 0.028 (0.025–0.031), respectively. Hepatitis C mortality rates were 4-fold higher than those associated with hepatitis B [1.964 (1.940–1.989) vs 0.500 (0.488–0.512)]. South region had the higher rates for hepatitis C [3.163 (3.087–3.241)] and North had the higher rates for hepatitis A [0.066 (0.049–0.087)], B [0.986 (0.918–1.058)] and Delta [0.220 (0.190–0.253)]. Conclusion Viral hepatitis remains a major public health issue in Brazil. Mortality rates were not homogeneous across the country, suggesting that health policies should be customized according to geographical location.http://link.springer.com/article/10.1186/s12879-017-2619-yLiver diseaseHepatitisDeath ratesAge-standardized mortality |
| spellingShingle | Hugo Perazzo Antonio G Pacheco Paula M Luz Rodolfo Castro Chris Hyde Juliana Fittipaldi Caroline Rigolon Sandra W Cardoso Beatriz Grinsztejn Valdiléa G Veloso Age-standardized mortality rates related to viral hepatitis in Brazil BMC Infectious Diseases Liver disease Hepatitis Death rates Age-standardized mortality |
| title | Age-standardized mortality rates related to viral hepatitis in Brazil |
| title_full | Age-standardized mortality rates related to viral hepatitis in Brazil |
| title_fullStr | Age-standardized mortality rates related to viral hepatitis in Brazil |
| title_full_unstemmed | Age-standardized mortality rates related to viral hepatitis in Brazil |
| title_short | Age-standardized mortality rates related to viral hepatitis in Brazil |
| title_sort | age standardized mortality rates related to viral hepatitis in brazil |
| topic | Liver disease Hepatitis Death rates Age-standardized mortality |
| url | http://link.springer.com/article/10.1186/s12879-017-2619-y |
| work_keys_str_mv | AT hugoperazzo agestandardizedmortalityratesrelatedtoviralhepatitisinbrazil AT antoniogpacheco agestandardizedmortalityratesrelatedtoviralhepatitisinbrazil AT paulamluz agestandardizedmortalityratesrelatedtoviralhepatitisinbrazil AT rodolfocastro agestandardizedmortalityratesrelatedtoviralhepatitisinbrazil AT chrishyde agestandardizedmortalityratesrelatedtoviralhepatitisinbrazil AT julianafittipaldi agestandardizedmortalityratesrelatedtoviralhepatitisinbrazil AT carolinerigolon agestandardizedmortalityratesrelatedtoviralhepatitisinbrazil AT sandrawcardoso agestandardizedmortalityratesrelatedtoviralhepatitisinbrazil AT beatrizgrinsztejn agestandardizedmortalityratesrelatedtoviralhepatitisinbrazil AT valdileagveloso agestandardizedmortalityratesrelatedtoviralhepatitisinbrazil |