The Unexpected Anabolic Phenotype and Extended Longevity of Skin Fibroblasts after Chronic Glucocorticoid Excess

Intense stress can challenge tissue homeostasis and accelerate the ageing process. However, several lines of evidence indicate that repeated mild stresses can have beneficial and even life-prolonging effects. Hypersecretion of glucocorticoids (GC) represents the major hormonal response to stress. Be...

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Bibliographic Details
Main Authors: Harris Pratsinis, Stylianos Tsagarakis, Irene Zervolea, Dimitri Stathakos, Nikos Thalassinos, Dimitris Kletsas
Format: Article
Language:English
Published: SAGE Publishing 2006-04-01
Series:Dose-Response
Online Access:https://doi.org/10.2203/dose-response.05-007.Pratsinis

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