Human papillomavirus infection and fertility alteration: a systematic review.

HPV is the most prevalent sexually transmitted infection and its effect in cancer induction is well documented. HPV infections are mostly asymptomatic, but it is unclear whether HPV infections can result in alterations of reproductive health.To determine the relationship between human papillomavirus...

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Main Authors: Tiatou Souho, Mohamed Benlemlih, Bahia Bennani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4436317?pdf=render
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author Tiatou Souho
Mohamed Benlemlih
Bahia Bennani
author_facet Tiatou Souho
Mohamed Benlemlih
Bahia Bennani
author_sort Tiatou Souho
collection DOAJ
description HPV is the most prevalent sexually transmitted infection and its effect in cancer induction is well documented. HPV infections are mostly asymptomatic, but it is unclear whether HPV infections can result in alterations of reproductive health.To determine the relationship between human papillomavirus infections and reproductive health in both men and women.A systematic literature review was performed in PubMed and ScienceDirect data bases from January 1994 through August 2014.HPV infections are shown to be significantly associated to many adverse effects in the reproductive function. These adverse effects were reported in different levels from cells production to pregnancy and may be related to the infecting genotype.It appears from this study that HPV detection and genotyping could be of great value in infertility diagnosis at least in idiopathic infertility cases. Like for the risk of carcinogenesis, another classification of HPV regarding the risk of fertility alteration may be considered after deep investigations.
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spelling doaj.art-bb72d487c3bc423f9cef5761dfc327272022-12-22T02:33:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01105e012693610.1371/journal.pone.0126936Human papillomavirus infection and fertility alteration: a systematic review.Tiatou SouhoMohamed BenlemlihBahia BennaniHPV is the most prevalent sexually transmitted infection and its effect in cancer induction is well documented. HPV infections are mostly asymptomatic, but it is unclear whether HPV infections can result in alterations of reproductive health.To determine the relationship between human papillomavirus infections and reproductive health in both men and women.A systematic literature review was performed in PubMed and ScienceDirect data bases from January 1994 through August 2014.HPV infections are shown to be significantly associated to many adverse effects in the reproductive function. These adverse effects were reported in different levels from cells production to pregnancy and may be related to the infecting genotype.It appears from this study that HPV detection and genotyping could be of great value in infertility diagnosis at least in idiopathic infertility cases. Like for the risk of carcinogenesis, another classification of HPV regarding the risk of fertility alteration may be considered after deep investigations.http://europepmc.org/articles/PMC4436317?pdf=render
spellingShingle Tiatou Souho
Mohamed Benlemlih
Bahia Bennani
Human papillomavirus infection and fertility alteration: a systematic review.
PLoS ONE
title Human papillomavirus infection and fertility alteration: a systematic review.
title_full Human papillomavirus infection and fertility alteration: a systematic review.
title_fullStr Human papillomavirus infection and fertility alteration: a systematic review.
title_full_unstemmed Human papillomavirus infection and fertility alteration: a systematic review.
title_short Human papillomavirus infection and fertility alteration: a systematic review.
title_sort human papillomavirus infection and fertility alteration a systematic review
url http://europepmc.org/articles/PMC4436317?pdf=render
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