Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives
There is a well-known inverse association between mortality rate from infectious diseases and improvements in socioeconomic status, even though longer time-series are required to demonstrate this relationship. This general rule seems to apply to mortality from pneumonia in children in the pneumococc...
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Format: | Article |
Language: | English |
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Taylor & Francis Group
2021-02-01
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Series: | Human Vaccines & Immunotherapeutics |
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Online Access: | http://dx.doi.org/10.1080/21645515.2020.1787071 |
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author | Paulo Camargos Linjie Zhang Cristiana M. Nascimento-Carvalho |
author_facet | Paulo Camargos Linjie Zhang Cristiana M. Nascimento-Carvalho |
author_sort | Paulo Camargos |
collection | DOAJ |
description | There is a well-known inverse association between mortality rate from infectious diseases and improvements in socioeconomic status, even though longer time-series are required to demonstrate this relationship. This general rule seems to apply to mortality from pneumonia in children in the pneumococcal conjugate vaccine (PCV) era. Two recent published secular trend studies spanning from about 30 years among Brazilians under the age of five show either no effect of PCV – not even death rate decline from pneumococcal meningitis – or a modest one (8% reduction). Time-series mortality studies from pneumonia are needed for both, developed and developing countries, those who have implemented PCV or not. Results from these studies would provide critical input and feedback to public health policy makers. |
first_indexed | 2024-03-11T22:42:43Z |
format | Article |
id | doaj.art-bb75dd6d039040709891bb15a26e1605 |
institution | Directory Open Access Journal |
issn | 2164-5515 2164-554X |
language | English |
last_indexed | 2024-03-11T22:42:43Z |
publishDate | 2021-02-01 |
publisher | Taylor & Francis Group |
record_format | Article |
series | Human Vaccines & Immunotherapeutics |
spelling | doaj.art-bb75dd6d039040709891bb15a26e16052023-09-22T08:51:50ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2021-02-0117253754510.1080/21645515.2020.17870711787071Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fivesPaulo Camargos0Linjie Zhang1Cristiana M. Nascimento-Carvalho2University Hospital, Federal University of Minas GeraisFederal University of Rio GrandeFederal University of BahiaThere is a well-known inverse association between mortality rate from infectious diseases and improvements in socioeconomic status, even though longer time-series are required to demonstrate this relationship. This general rule seems to apply to mortality from pneumonia in children in the pneumococcal conjugate vaccine (PCV) era. Two recent published secular trend studies spanning from about 30 years among Brazilians under the age of five show either no effect of PCV – not even death rate decline from pneumococcal meningitis – or a modest one (8% reduction). Time-series mortality studies from pneumonia are needed for both, developed and developing countries, those who have implemented PCV or not. Results from these studies would provide critical input and feedback to public health policy makers.http://dx.doi.org/10.1080/21645515.2020.1787071pneumococcal conjugate vaccinespneumoniallower respiratory infectionsmortalitychildren |
spellingShingle | Paulo Camargos Linjie Zhang Cristiana M. Nascimento-Carvalho Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives Human Vaccines & Immunotherapeutics pneumococcal conjugate vaccines pneumonial lower respiratory infections mortality children |
title | Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives |
title_full | Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives |
title_fullStr | Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives |
title_full_unstemmed | Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives |
title_short | Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives |
title_sort | effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under fives |
topic | pneumococcal conjugate vaccines pneumonial lower respiratory infections mortality children |
url | http://dx.doi.org/10.1080/21645515.2020.1787071 |
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