Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives

There is a well-known inverse association between mortality rate from infectious diseases and improvements in socioeconomic status, even though longer time-series are required to demonstrate this relationship. This general rule seems to apply to mortality from pneumonia in children in the pneumococc...

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Main Authors: Paulo Camargos, Linjie Zhang, Cristiana M. Nascimento-Carvalho
Format: Article
Language:English
Published: Taylor & Francis Group 2021-02-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2020.1787071
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author Paulo Camargos
Linjie Zhang
Cristiana M. Nascimento-Carvalho
author_facet Paulo Camargos
Linjie Zhang
Cristiana M. Nascimento-Carvalho
author_sort Paulo Camargos
collection DOAJ
description There is a well-known inverse association between mortality rate from infectious diseases and improvements in socioeconomic status, even though longer time-series are required to demonstrate this relationship. This general rule seems to apply to mortality from pneumonia in children in the pneumococcal conjugate vaccine (PCV) era. Two recent published secular trend studies spanning from about 30 years among Brazilians under the age of five show either no effect of PCV – not even death rate decline from pneumococcal meningitis – or a modest one (8% reduction). Time-series mortality studies from pneumonia are needed for both, developed and developing countries, those who have implemented PCV or not. Results from these studies would provide critical input and feedback to public health policy makers.
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spelling doaj.art-bb75dd6d039040709891bb15a26e16052023-09-22T08:51:50ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2021-02-0117253754510.1080/21645515.2020.17870711787071Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fivesPaulo Camargos0Linjie Zhang1Cristiana M. Nascimento-Carvalho2University Hospital, Federal University of Minas GeraisFederal University of Rio GrandeFederal University of BahiaThere is a well-known inverse association between mortality rate from infectious diseases and improvements in socioeconomic status, even though longer time-series are required to demonstrate this relationship. This general rule seems to apply to mortality from pneumonia in children in the pneumococcal conjugate vaccine (PCV) era. Two recent published secular trend studies spanning from about 30 years among Brazilians under the age of five show either no effect of PCV – not even death rate decline from pneumococcal meningitis – or a modest one (8% reduction). Time-series mortality studies from pneumonia are needed for both, developed and developing countries, those who have implemented PCV or not. Results from these studies would provide critical input and feedback to public health policy makers.http://dx.doi.org/10.1080/21645515.2020.1787071pneumococcal conjugate vaccinespneumoniallower respiratory infectionsmortalitychildren
spellingShingle Paulo Camargos
Linjie Zhang
Cristiana M. Nascimento-Carvalho
Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives
Human Vaccines & Immunotherapeutics
pneumococcal conjugate vaccines
pneumonial
lower respiratory infections
mortality
children
title Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives
title_full Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives
title_fullStr Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives
title_full_unstemmed Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives
title_short Effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under-fives
title_sort effect of pneumococcal conjugate vaccines on mortality from lower respiratory infections and pneumonia among under fives
topic pneumococcal conjugate vaccines
pneumonial
lower respiratory infections
mortality
children
url http://dx.doi.org/10.1080/21645515.2020.1787071
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