RRM2 Alleviates Doxorubicin-Induced Cardiotoxicity through the AKT/mTOR Signaling Pathway

Doxorubicin (DOX) is an effective chemotherapeutic agent that plays an unparalleled role in cancer treatment. However, its serious dose-dependent cardiotoxicity, which eventually contributes to irreversible heart failure, has greatly limited the widespread clinical application of DOX. A previous stu...

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Chi tiết về thư mục
Những tác giả chính: Yuheng Jiao, Yanyan Li, Jiayan Zhang, Song Zhang, Yafang Zha, Jian Wang
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: MDPI AG 2022-02-01
Loạt:Biomolecules
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Truy cập trực tuyến:https://www.mdpi.com/2218-273X/12/2/299