B cell‐activating factors in autoimmune pulmonary alveolar proteinosis

B cell‐activating factors in autoimmune pulmonary alveolar proteinosis

Abstract Background Autoimmune pulmonary alveolar proteinosis (APAP) results from the suppression of granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling by a neutralizing autoantibody against GM-CSF. B cell-activating factor (BAFF) and a proliferation-inducing ligand (APRIL) are invo...

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Bibliographic Details
Main Authors: Masaki Hirose, Toru Arai, Chikatoshi Sugimoto, Takayuki Takimoto, Reiko Sugawara, Shojiro Minomo, Sayoko Shintani, Naoko Takeuchi, Kanako Katayama, Yasushi Inoue, Tomoko Kagawa, Takahiko Kasai, Masanori Akira, Yoshikazu Inoue
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Autoimmune pulmonary alveolar proteinosis
B cell‐activating factor
Biomarker
Online Access:https://doi.org/10.1186/s13023-021-01755-y

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