The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.
Endothelial dysfunction is common in acute and chronic organ injury. Isoflurane is a widely used halogenated volatile anesthetic during the perioperative period and protects against endothelial cell death and inflammation. In this study, we tested whether isoflurane induces endothelial ecto-5'-...
Hlavní autoři: | , , , , |
---|---|
Médium: | Článek |
Jazyk: | English |
Vydáno: |
Public Library of Science (PLoS)
2014-01-01
|
Edice: | PLoS ONE |
On-line přístup: | http://europepmc.org/articles/PMC4063779?pdf=render |