The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.
Endothelial dysfunction is common in acute and chronic organ injury. Isoflurane is a widely used halogenated volatile anesthetic during the perioperative period and protects against endothelial cell death and inflammation. In this study, we tested whether isoflurane induces endothelial ecto-5'-...
Autors principals: | Mihwa Kim, Ahrom Ham, Katelyn Yu-Mi Kim, Kevin M Brown, H Thomas Lee |
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Format: | Article |
Idioma: | English |
Publicat: |
Public Library of Science (PLoS)
2014-01-01
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Col·lecció: | PLoS ONE |
Accés en línia: | http://europepmc.org/articles/PMC4063779?pdf=render |
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