The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.
Endothelial dysfunction is common in acute and chronic organ injury. Isoflurane is a widely used halogenated volatile anesthetic during the perioperative period and protects against endothelial cell death and inflammation. In this study, we tested whether isoflurane induces endothelial ecto-5'-...
Hlavní autoři: | Mihwa Kim, Ahrom Ham, Katelyn Yu-Mi Kim, Kevin M Brown, H Thomas Lee |
---|---|
Médium: | Článek |
Jazyk: | English |
Vydáno: |
Public Library of Science (PLoS)
2014-01-01
|
Edice: | PLoS ONE |
On-line přístup: | http://europepmc.org/articles/PMC4063779?pdf=render |
Podobné jednotky
-
Extracellular Adenosine Formation by Ecto-5'-Nucleotidase (CD73) Is No Essential Trigger for Early Phase Ischemic Preconditioning.
Autor: Georg Wolff, a další
Vydáno: (2015-01-01) -
High Expression of Ecto-Nucleotidases CD39 and CD73 in Human Endometrial Tumors
Autor: Elisabet Aliagas, a další
Vydáno: (2014-01-01) -
Autoimmunity in CD73/Ecto-5'-nucleotidase deficient mice induces renal injury.
Autor: Cornelia Blume, a další
Vydáno: (2012-01-01) -
Identification of allosteric inhibitors of the ecto-5'-nucleotidase (CD73) targeting the dimer interface.
Autor: Rahila Rahimova, a další
Vydáno: (2018-01-01) -
Regulation of Ecto-5´-Nucleotidase by Docosahexaenoic Acid in Human Endothelial Cells
Autor: Vu Thi Thom, a další
Vydáno: (2013-08-01)