The volatile anesthetic isoflurane increases endothelial adenosine generation via microparticle ecto-5'-nucleotidase (CD73) release.
Endothelial dysfunction is common in acute and chronic organ injury. Isoflurane is a widely used halogenated volatile anesthetic during the perioperative period and protects against endothelial cell death and inflammation. In this study, we tested whether isoflurane induces endothelial ecto-5'-...
Κύριοι συγγραφείς: | Mihwa Kim, Ahrom Ham, Katelyn Yu-Mi Kim, Kevin M Brown, H Thomas Lee |
---|---|
Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
Public Library of Science (PLoS)
2014-01-01
|
Σειρά: | PLoS ONE |
Διαθέσιμο Online: | http://europepmc.org/articles/PMC4063779?pdf=render |
Παρόμοια τεκμήρια
-
Extracellular Adenosine Formation by Ecto-5'-Nucleotidase (CD73) Is No Essential Trigger for Early Phase Ischemic Preconditioning.
ανά: Georg Wolff, κ.ά.
Έκδοση: (2015-01-01) -
High Expression of Ecto-Nucleotidases CD39 and CD73 in Human Endometrial Tumors
ανά: Elisabet Aliagas, κ.ά.
Έκδοση: (2014-01-01) -
Autoimmunity in CD73/Ecto-5'-nucleotidase deficient mice induces renal injury.
ανά: Cornelia Blume, κ.ά.
Έκδοση: (2012-01-01) -
Identification of allosteric inhibitors of the ecto-5'-nucleotidase (CD73) targeting the dimer interface.
ανά: Rahila Rahimova, κ.ά.
Έκδοση: (2018-01-01) -
Regulation of Ecto-5´-Nucleotidase by Docosahexaenoic Acid in Human Endothelial Cells
ανά: Vu Thi Thom, κ.ά.
Έκδοση: (2013-08-01)