Microscopical characteristics, phytochemical investigation and biological activities of different Lysimachia species growing in Vietnam
Several species of the genus Lysimachia L. (Primulaceae) are well known in folk medicine, but very few studies have been conducted on them. The aim of our study was to investigate the microscopical characteristics and chemical composition of Lysimachia insignis Hemsl., L. decurrens G. Forst., and L...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
AcademicPres
2022-06-01
|
| Series: | Notulae Botanicae Horti Agrobotanici Cluj-Napoca |
| Subjects: | |
| Online Access: | https://www.notulaebotanicae.ro/index.php/nbha/article/view/12692 |
| _version_ | 1811318880325337088 |
|---|---|
| author | Quang Hung NGUYEN Thanh Tung NGUYEN Viet Than NGUYEN Minh Ha LE Ain RAAL |
| author_facet | Quang Hung NGUYEN Thanh Tung NGUYEN Viet Than NGUYEN Minh Ha LE Ain RAAL |
| author_sort | Quang Hung NGUYEN |
| collection | DOAJ |
| description |
Several species of the genus Lysimachia L. (Primulaceae) are well known in folk medicine, but very few studies have been conducted on them. The aim of our study was to investigate the microscopical characteristics and chemical composition of Lysimachia insignis Hemsl., L. decurrens G. Forst., and L. congestiflora Hemsl. as well as to evaluate some biological activities of their methanol extracts. The transverse sections of stem and powder characteristics of the three Lysimachia species shared some similarities. Also, some differences were indicated. The chemical investigation of three aforesaid species including the preliminary phytochemical screening, the quantification of the total polyphenol content and total flavonoid content, as well as the determination of metabolites. The phytochemical screening showed the presence of flavonoids, saponins, tannins and sterols in all the three species. On the other hand, coumarins were detected in L. insignis while anthranoids were present in L. decurrens and L. congestiflora. The total polyphenol content and the total flavonoid content of the aforesaid species were determined by the spectrometric method. The metabolite profiling approach of three species was performed by LC-Q-ToF-HRMS and HPTLC. The methanol extract of L. insignis showed a weak inhibitory effect on NO production (I% = 57.4 at the concentration of 100 µg/ml) while the extract of L. decurrens exhibited moderate anti-oxidant activity in vitro (SC% = 62.5 at the concentration of 100 µg/mL).
|
| first_indexed | 2024-04-13T12:32:56Z |
| format | Article |
| id | doaj.art-bb84f1715fb74474b3b1fe5159ddb386 |
| institution | Directory Open Access Journal |
| issn | 0255-965X 1842-4309 |
| language | English |
| last_indexed | 2024-04-13T12:32:56Z |
| publishDate | 2022-06-01 |
| publisher | AcademicPres |
| record_format | Article |
| series | Notulae Botanicae Horti Agrobotanici Cluj-Napoca |
| spelling | doaj.art-bb84f1715fb74474b3b1fe5159ddb3862022-12-22T02:46:47ZengAcademicPresNotulae Botanicae Horti Agrobotanici Cluj-Napoca0255-965X1842-43092022-06-0150210.15835/nbha50212692Microscopical characteristics, phytochemical investigation and biological activities of different Lysimachia species growing in VietnamQuang Hung NGUYEN0Thanh Tung NGUYEN1Viet Than NGUYEN2Minh Ha LE3Ain RAAL4Vietnam Academy of Science and Technology (VAST), Institute of Ecology and Biological Resources, Hoang Quoc Viet 18, Ha Noi; Graduate University of Science and Technology, VAST, Hoang Quoc Viet 18, Ha NoiHanoi University of Pharmacy, Department of Pharmacognosy, Le Thanh Tong 15, Ha NoiHanoi University of Pharmacy, Department of Pharmacognosy, Le Thanh Tong 15, Ha NoiVietnam Academy of Science and Technology (VAST), Institute of Natural Products Chemistry, Hoang Quoc Viet 18, Ha NoiUniversity of Tartu, Institute of Pharmacy, Faculty of Medicine, Nooruse 1, Tartu 50411 Several species of the genus Lysimachia L. (Primulaceae) are well known in folk medicine, but very few studies have been conducted on them. The aim of our study was to investigate the microscopical characteristics and chemical composition of Lysimachia insignis Hemsl., L. decurrens G. Forst., and L. congestiflora Hemsl. as well as to evaluate some biological activities of their methanol extracts. The transverse sections of stem and powder characteristics of the three Lysimachia species shared some similarities. Also, some differences were indicated. The chemical investigation of three aforesaid species including the preliminary phytochemical screening, the quantification of the total polyphenol content and total flavonoid content, as well as the determination of metabolites. The phytochemical screening showed the presence of flavonoids, saponins, tannins and sterols in all the three species. On the other hand, coumarins were detected in L. insignis while anthranoids were present in L. decurrens and L. congestiflora. The total polyphenol content and the total flavonoid content of the aforesaid species were determined by the spectrometric method. The metabolite profiling approach of three species was performed by LC-Q-ToF-HRMS and HPTLC. The methanol extract of L. insignis showed a weak inhibitory effect on NO production (I% = 57.4 at the concentration of 100 µg/ml) while the extract of L. decurrens exhibited moderate anti-oxidant activity in vitro (SC% = 62.5 at the concentration of 100 µg/mL). https://www.notulaebotanicae.ro/index.php/nbha/article/view/12692biological activity;characteristics of stems and leavesLysimachiametabolitespowder characteristics |
| spellingShingle | Quang Hung NGUYEN Thanh Tung NGUYEN Viet Than NGUYEN Minh Ha LE Ain RAAL Microscopical characteristics, phytochemical investigation and biological activities of different Lysimachia species growing in Vietnam Notulae Botanicae Horti Agrobotanici Cluj-Napoca biological activity; characteristics of stems and leaves Lysimachia metabolites powder characteristics |
| title | Microscopical characteristics, phytochemical investigation and biological activities of different Lysimachia species growing in Vietnam |
| title_full | Microscopical characteristics, phytochemical investigation and biological activities of different Lysimachia species growing in Vietnam |
| title_fullStr | Microscopical characteristics, phytochemical investigation and biological activities of different Lysimachia species growing in Vietnam |
| title_full_unstemmed | Microscopical characteristics, phytochemical investigation and biological activities of different Lysimachia species growing in Vietnam |
| title_short | Microscopical characteristics, phytochemical investigation and biological activities of different Lysimachia species growing in Vietnam |
| title_sort | microscopical characteristics phytochemical investigation and biological activities of different lysimachia species growing in vietnam |
| topic | biological activity; characteristics of stems and leaves Lysimachia metabolites powder characteristics |
| url | https://www.notulaebotanicae.ro/index.php/nbha/article/view/12692 |
| work_keys_str_mv | AT quanghungnguyen microscopicalcharacteristicsphytochemicalinvestigationandbiologicalactivitiesofdifferentlysimachiaspeciesgrowinginvietnam AT thanhtungnguyen microscopicalcharacteristicsphytochemicalinvestigationandbiologicalactivitiesofdifferentlysimachiaspeciesgrowinginvietnam AT vietthannguyen microscopicalcharacteristicsphytochemicalinvestigationandbiologicalactivitiesofdifferentlysimachiaspeciesgrowinginvietnam AT minhhale microscopicalcharacteristicsphytochemicalinvestigationandbiologicalactivitiesofdifferentlysimachiaspeciesgrowinginvietnam AT ainraal microscopicalcharacteristicsphytochemicalinvestigationandbiologicalactivitiesofdifferentlysimachiaspeciesgrowinginvietnam |