Androgen receptor molecular biology and potential targets in prostate cancer
The androgen receptor (AR) is a key transcriptional regulator and therapeutic target in prostate cancer. During androgen deprivation therapy to treat metastatic prostate cancer, surviving cells acquire increased AR signaling through a variety of mechanisms, one of which is enhanced interactions with...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2010-06-01
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| Series: | Therapeutic Advances in Urology |
| Online Access: | https://doi.org/10.1177/1756287210372380 |