Echocardiographic Measurements in a Preclinical Model of Chronic Chagasic Cardiomyopathy in Dogs: Validation and Reproducibility

Echocardiographic Measurements in a Preclinical Model of Chronic Chagasic Cardiomyopathy in Dogs: Validation and Reproducibility

Background: The failure to translate preclinical results to the clinical setting is the rule, not the exception. One reason that is frequently overlooked is whether the animal model reproduces distinctive features of human disease. Another is the reproducibility of the method used to measure treatme...

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Bibliographic Details
Main Authors: Eduardo B. Carvalho, Isalira P. R. Ramos, Alvaro F. S. Nascimento, Guilherme V. Brasil, Debora B. Mello, Martin Oti, Michael Sammeth, Maria T. Bahia, Antonio C. Campos de Carvalho, Adriana B. Carvalho
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Chagas disease
chagasic cardiomyopathy
canine model
dogs
systolic dysfunction
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00332/full

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