<i>GBA</i> Variants and Parkinson Disease: Mechanisms and Treatments
The <i>GBA</i> gene encodes for the lysosomal enzyme glucocerebrosidase (GCase), which maintains glycosphingolipid homeostasis. Approximately 5–15% of PD patients have mutations in the <i>GBA</i> gene, making it numerically the most important genetic risk factor for Parkinson...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
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| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/11/8/1261 |