Novel anticarcinoembryonic antigen antibody–drug conjugate has antitumor activity in the existence of soluble antigen

Novel anticarcinoembryonic antigen antibody–drug conjugate has antitumor activity in the existence of soluble antigen

Abstract Carcinoembryonic antigen (CEA) is a classic tumor‐specific antigen that is overexpressed in several cancers, including gastric cancer. Although some anti‐CEA antibodies have been tested, to the best of our knowledge, there are currently no clinically approved anti‐CEA antibody therapies. Be...

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Bibliographic Details
Main Authors: Daisuke Shinmi, Ryosuke Nakano, Keisuke Mitamura, Minami Suzuki‐Imaizumi, Junko Iwano, Yuya Isoda, Junichi Enokizono, Yasuhisa Shiraishi, Emi Arakawa, Kazuma Tomizuka, Kazuhiro Masuda
Format: Article
Language:English
Published: Wiley 2017-04-01
Series:Cancer Medicine
Subjects:
Antibody
antibody–drug conjugate
CEA
esophageal cancer
gastric cancer
Online Access:https://doi.org/10.1002/cam4.1003

Internet

https://doi.org/10.1002/cam4.1003

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