A synthetic biochemistry platform for cell free production of monoterpenes from glucose
Terpenes are bioactive natural products derived from plants with several commercial applications. Here, the authors engineer a cell-free system composed of 27 enzymes that convert glucose into terpenes, highlighting the potential of synthetic biochemistry approaches for biocompounds production.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2017-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms15526 |
| _version_ | 1818977666452160512 |
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| author | Tyler P. Korman Paul H. Opgenorth James U. Bowie |
| author_facet | Tyler P. Korman Paul H. Opgenorth James U. Bowie |
| author_sort | Tyler P. Korman |
| collection | DOAJ |
| description | Terpenes are bioactive natural products derived from plants with several commercial applications. Here, the authors engineer a cell-free system composed of 27 enzymes that convert glucose into terpenes, highlighting the potential of synthetic biochemistry approaches for biocompounds production. |
| first_indexed | 2024-12-20T16:31:22Z |
| format | Article |
| id | doaj.art-bb8ace10bdcb41a5a7a1b989f4dffc78 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T16:31:22Z |
| publishDate | 2017-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-bb8ace10bdcb41a5a7a1b989f4dffc782022-12-21T19:33:15ZengNature PortfolioNature Communications2041-17232017-05-01811810.1038/ncomms15526A synthetic biochemistry platform for cell free production of monoterpenes from glucoseTyler P. Korman0Paul H. Opgenorth1James U. Bowie2Department of Chemistry and Biochemistry, UCLA-DOE Institute, Molecular Biology Institute, University of CaliforniaDepartment of Chemistry and Biochemistry, UCLA-DOE Institute, Molecular Biology Institute, University of CaliforniaDepartment of Chemistry and Biochemistry, UCLA-DOE Institute, Molecular Biology Institute, University of CaliforniaTerpenes are bioactive natural products derived from plants with several commercial applications. Here, the authors engineer a cell-free system composed of 27 enzymes that convert glucose into terpenes, highlighting the potential of synthetic biochemistry approaches for biocompounds production.https://doi.org/10.1038/ncomms15526 |
| spellingShingle | Tyler P. Korman Paul H. Opgenorth James U. Bowie A synthetic biochemistry platform for cell free production of monoterpenes from glucose Nature Communications |
| title | A synthetic biochemistry platform for cell free production of monoterpenes from glucose |
| title_full | A synthetic biochemistry platform for cell free production of monoterpenes from glucose |
| title_fullStr | A synthetic biochemistry platform for cell free production of monoterpenes from glucose |
| title_full_unstemmed | A synthetic biochemistry platform for cell free production of monoterpenes from glucose |
| title_short | A synthetic biochemistry platform for cell free production of monoterpenes from glucose |
| title_sort | synthetic biochemistry platform for cell free production of monoterpenes from glucose |
| url | https://doi.org/10.1038/ncomms15526 |
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