Liver disease in pregnancy

Deranged liver function tests are encountered in 3% of pregnancies. The potential causes are classified as those unique to and those just incidental to pregnancy. Pregnancy-related diseases are the most frequent causes of liver dysfunction during pregnancy and exhibit a trimester-specific occurrence...

Full description

Bibliographic Details
Main Authors: Shashank Shekhar, Gaurav Diddi
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455915001503
_version_ 1818192772204593152
author Shashank Shekhar
Gaurav Diddi
author_facet Shashank Shekhar
Gaurav Diddi
author_sort Shashank Shekhar
collection DOAJ
description Deranged liver function tests are encountered in 3% of pregnancies. The potential causes are classified as those unique to and those just incidental to pregnancy. Pregnancy-related diseases are the most frequent causes of liver dysfunction during pregnancy and exhibit a trimester-specific occurrence during pregnancy. Differentiation of liver dysfunction as that related to and just incidental to pregnancy is the key to management, especially when liver dysfunction is encountered after 28 weeks of pregnancy. It can be judged from the fact that delivery remains the cornerstone of management of pregnancy-related diseases except hyperemesis gravidarum. This is an overview of the causes of liver dysfunction during pregnancy; an update on the underlying mechanisms of their occurrence, especially liver diseases unique to pregnancy; and a methodological approach to their diagnosis and management.
first_indexed 2024-12-12T00:35:49Z
format Article
id doaj.art-bb8f0a5f03de4cfd92e4ade4f44449d0
institution Directory Open Access Journal
issn 1028-4559
language English
last_indexed 2024-12-12T00:35:49Z
publishDate 2015-10-01
publisher Elsevier
record_format Article
series Taiwanese Journal of Obstetrics & Gynecology
spelling doaj.art-bb8f0a5f03de4cfd92e4ade4f44449d02022-12-22T00:44:22ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592015-10-0154547548210.1016/j.tjog.2015.01.004Liver disease in pregnancyShashank Shekhar0Gaurav Diddi1Department of Obstetrics & Gynecology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaDepartment of Gastroenterology, Max Superspeciality Hospital, Mohali, Punjab, IndiaDeranged liver function tests are encountered in 3% of pregnancies. The potential causes are classified as those unique to and those just incidental to pregnancy. Pregnancy-related diseases are the most frequent causes of liver dysfunction during pregnancy and exhibit a trimester-specific occurrence during pregnancy. Differentiation of liver dysfunction as that related to and just incidental to pregnancy is the key to management, especially when liver dysfunction is encountered after 28 weeks of pregnancy. It can be judged from the fact that delivery remains the cornerstone of management of pregnancy-related diseases except hyperemesis gravidarum. This is an overview of the causes of liver dysfunction during pregnancy; an update on the underlying mechanisms of their occurrence, especially liver diseases unique to pregnancy; and a methodological approach to their diagnosis and management.http://www.sciencedirect.com/science/article/pii/S1028455915001503Liver diseasespregnancycholestasis pregnancyHELLP
spellingShingle Shashank Shekhar
Gaurav Diddi
Liver disease in pregnancy
Taiwanese Journal of Obstetrics & Gynecology
Liver diseases
pregnancy
cholestasis pregnancy
HELLP
title Liver disease in pregnancy
title_full Liver disease in pregnancy
title_fullStr Liver disease in pregnancy
title_full_unstemmed Liver disease in pregnancy
title_short Liver disease in pregnancy
title_sort liver disease in pregnancy
topic Liver diseases
pregnancy
cholestasis pregnancy
HELLP
url http://www.sciencedirect.com/science/article/pii/S1028455915001503
work_keys_str_mv AT shashankshekhar liverdiseaseinpregnancy
AT gauravdiddi liverdiseaseinpregnancy