The comparison of levobupivacaine in continuous or single dose spinal anesthesia for transurethral resection of prostate surgery

Background: The aim of the study is to compare the efficacy of levobupivacaine induced continuous spinal anesthesia (CSA) versus single dose spinal anesthesia (SDSA) in patients who are planned to undergo transurethral prostate resection. Methods: Sixty years or older, ASA I–II or III, 50 patients w...

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Main Authors: Yunus Baydilek, Bülent Serhan Yurtlu, Volkan Hanci, Hilal Ayoğlu, Rahşan Dilek Okyay, Gulay Erdoğan Kayhan, Hüsnü Tokgöz, Görkem Mungan, Işıl Özkoçak
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Brazilian Journal of Anesthesiology
Online Access:http://www.sciencedirect.com/science/article/pii/S0104001413001279
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author Yunus Baydilek
Bülent Serhan Yurtlu
Volkan Hanci
Hilal Ayoğlu
Rahşan Dilek Okyay
Gulay Erdoğan Kayhan
Hüsnü Tokgöz
Görkem Mungan
Işıl Özkoçak
author_facet Yunus Baydilek
Bülent Serhan Yurtlu
Volkan Hanci
Hilal Ayoğlu
Rahşan Dilek Okyay
Gulay Erdoğan Kayhan
Hüsnü Tokgöz
Görkem Mungan
Işıl Özkoçak
author_sort Yunus Baydilek
collection DOAJ
description Background: The aim of the study is to compare the efficacy of levobupivacaine induced continuous spinal anesthesia (CSA) versus single dose spinal anesthesia (SDSA) in patients who are planned to undergo transurethral prostate resection. Methods: Sixty years or older, ASA I–II or III, 50 patients were included in the study. 12.5 mg 0.5% levobupivacaine were administered intrathecally in SDSA group. In CSA group, initially 2 mL of 0.25% levobupivacaine were administered through spinal catheter. In order to achieve sensory block level at T10 dermatome, additional 1 mL of 0.25% levobupivacaine were administered through the catheter in every 10 min. Hemodynamic parameters and block characteristics were recorded. Preoperative and postoperative blood samples of the patients were drawn to determine plasma cortisone and plasma epinephrine levels. Results: CSA technique provided better hemodynamic stability compared to SDSA technique particularly 90 min after intrathecal administration. The rise in sensory block level was rapid and the time to reach surgical anesthesia was shorter in SDSA group. Motor block developed faster in SDSA group. In CSA group, similar anesthesia level was achieved by using lower levobupivacaine dose and which was related to faster recovery. Although, both techniques were effective in preventing surgical stress respond, postoperative cortisone levels were suppressed more in SDSA group. Conclusion: CSA technique with 0.25% levobupivacaine can be used as a regional anesthesia method for elderly patients planned to have TUR-P operation. Keywords: Levobupivacaine, Continuous spinal anesthesia, Spinal anesthesia, Transurethral prostate resection
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spelling doaj.art-bb92445bebf741729368a54fbbe7010f2022-12-22T02:02:04ZengElsevierBrazilian Journal of Anesthesiology0104-00142014-03-016428997The comparison of levobupivacaine in continuous or single dose spinal anesthesia for transurethral resection of prostate surgeryYunus Baydilek0Bülent Serhan Yurtlu1Volkan Hanci2Hilal Ayoğlu3Rahşan Dilek Okyay4Gulay Erdoğan Kayhan5Hüsnü Tokgöz6Görkem Mungan7Işıl Özkoçak8Clinic of Anesthesiology Sani Konukoğlu Hospital, Gaziantep, TurkeyDepartment of Anesthesiology and Reanimation, Bulent Ecevit University, Zonguldak, Turkey; Corresponding author.Department of Anesthesiology and Reanimation, Çanakkale Onsekiz Mart University, Çanakkale, TurkeyDepartment of Anesthesiology and Reanimation, Bulent Ecevit University, Zonguldak, TurkeyDepartment of Anesthesiology and Reanimation, Bulent Ecevit University, Zonguldak, TurkeyDepartment of Anesthesiology and Reanimation, Inonü University, Zonguldak, TurkeyDepartment of Urology, Bulent Ecevit University, Zonguldak, TurkeyDepartment of Biochemistry, Bulent Ecevit University, Zonguldak, TurkeyDepartment of Anesthesiology and Reanimation, Bulent Ecevit University, Zonguldak, TurkeyBackground: The aim of the study is to compare the efficacy of levobupivacaine induced continuous spinal anesthesia (CSA) versus single dose spinal anesthesia (SDSA) in patients who are planned to undergo transurethral prostate resection. Methods: Sixty years or older, ASA I–II or III, 50 patients were included in the study. 12.5 mg 0.5% levobupivacaine were administered intrathecally in SDSA group. In CSA group, initially 2 mL of 0.25% levobupivacaine were administered through spinal catheter. In order to achieve sensory block level at T10 dermatome, additional 1 mL of 0.25% levobupivacaine were administered through the catheter in every 10 min. Hemodynamic parameters and block characteristics were recorded. Preoperative and postoperative blood samples of the patients were drawn to determine plasma cortisone and plasma epinephrine levels. Results: CSA technique provided better hemodynamic stability compared to SDSA technique particularly 90 min after intrathecal administration. The rise in sensory block level was rapid and the time to reach surgical anesthesia was shorter in SDSA group. Motor block developed faster in SDSA group. In CSA group, similar anesthesia level was achieved by using lower levobupivacaine dose and which was related to faster recovery. Although, both techniques were effective in preventing surgical stress respond, postoperative cortisone levels were suppressed more in SDSA group. Conclusion: CSA technique with 0.25% levobupivacaine can be used as a regional anesthesia method for elderly patients planned to have TUR-P operation. Keywords: Levobupivacaine, Continuous spinal anesthesia, Spinal anesthesia, Transurethral prostate resectionhttp://www.sciencedirect.com/science/article/pii/S0104001413001279
spellingShingle Yunus Baydilek
Bülent Serhan Yurtlu
Volkan Hanci
Hilal Ayoğlu
Rahşan Dilek Okyay
Gulay Erdoğan Kayhan
Hüsnü Tokgöz
Görkem Mungan
Işıl Özkoçak
The comparison of levobupivacaine in continuous or single dose spinal anesthesia for transurethral resection of prostate surgery
Brazilian Journal of Anesthesiology
title The comparison of levobupivacaine in continuous or single dose spinal anesthesia for transurethral resection of prostate surgery
title_full The comparison of levobupivacaine in continuous or single dose spinal anesthesia for transurethral resection of prostate surgery
title_fullStr The comparison of levobupivacaine in continuous or single dose spinal anesthesia for transurethral resection of prostate surgery
title_full_unstemmed The comparison of levobupivacaine in continuous or single dose spinal anesthesia for transurethral resection of prostate surgery
title_short The comparison of levobupivacaine in continuous or single dose spinal anesthesia for transurethral resection of prostate surgery
title_sort comparison of levobupivacaine in continuous or single dose spinal anesthesia for transurethral resection of prostate surgery
url http://www.sciencedirect.com/science/article/pii/S0104001413001279
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