Seroprevalence canine survey for selected vector-borne pathogens and its relationship with poverty in metropolitan Pereira, Colombia, 2020
Background: Tick-borne diseases (TBD) and dirofilariosis are currently not under surveillance in most Latin American countries. In addition, there is a significant lack of studies describing the current situation in most endemic areas, including Colombia. Therefore, seroprevalence studies are crucia...
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| Language: | English |
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Elsevier
2022-05-01
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| Series: | Parasite Epidemiology and Control |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405673122000137 |
| _version_ | 1818015173203460096 |
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| author | D. Katterine Bonilla-Aldana Erwin J. Gutiérrez-Grajales J. Paola Martínez-Arboleda María Angelica Reina-Mora Adrián E. Trejos-Mendoza Soffia Pérez-Vargas Lorenzo Valencia-Mejía Luisa F. Marín-Arboleda Daniela Osorio-Navia Mariana Chacón-Peña Luz Victoria González-Colonia Jaime A. Cardona-Ospina Erika Vanessa Jiménez-Posada Andrés Diaz Jean Carlos Salazar Manuel Sierra Fausto Muñoz-Lara Lysien I. Zambrano Eduardo Ramírez-Vallejo Juan Camilo Álvarez Ingrid Lorena Jaramillo-Delgado Samuel Pecho-Silva Alberto Paniz-Mondolfi Álvaro A. Faccini-Martínez Alfonso J. Rodríguez-Morales |
| author_facet | D. Katterine Bonilla-Aldana Erwin J. Gutiérrez-Grajales J. Paola Martínez-Arboleda María Angelica Reina-Mora Adrián E. Trejos-Mendoza Soffia Pérez-Vargas Lorenzo Valencia-Mejía Luisa F. Marín-Arboleda Daniela Osorio-Navia Mariana Chacón-Peña Luz Victoria González-Colonia Jaime A. Cardona-Ospina Erika Vanessa Jiménez-Posada Andrés Diaz Jean Carlos Salazar Manuel Sierra Fausto Muñoz-Lara Lysien I. Zambrano Eduardo Ramírez-Vallejo Juan Camilo Álvarez Ingrid Lorena Jaramillo-Delgado Samuel Pecho-Silva Alberto Paniz-Mondolfi Álvaro A. Faccini-Martínez Alfonso J. Rodríguez-Morales |
| author_sort | D. Katterine Bonilla-Aldana |
| collection | DOAJ |
| description | Background: Tick-borne diseases (TBD) and dirofilariosis are currently not under surveillance in most Latin American countries. In addition, there is a significant lack of studies describing the current situation in most endemic areas, including Colombia. Therefore, seroprevalence studies are crucial for understanding the epidemiology of these vector-borne diseases. Methods: A serosurvey for TBD and dirofilariosis among 100 dogs was carried out in the municipality of Pereira, located in the Coffee-Triangle region, Colombia. Samples were tested using a rapid assay test system (SNAP® 4Dx®); based on an enzyme immunoassay technique‚ screening for antibodies to Anaplasma phagocytophilum/platys (sensitivity 99.1%)‚ Borrelia burgdorferi s.l. (98.8%), and Ehrlichia canis/ewingii (96.2%) by using specific antigens and checking for Dirofilaria immitis antigen based on specific antibodies (99.2%). Bivariate analyses were performed on Stata®14, significant p < 0.05. Findings: Global seroprevalence to the selected vector-borne pathogens was 74% (95%CI 65–83%). The highest seroprevalence was found for E. canis/ewingii (74%), followed by A. phagocytophilum/platys (16%). Seropositivity for Borrelia spp. and Dirofilaria spp. was 0%. All Anaplasma spp. seropositive dogs showed co-detection of Ehrlichia spp. (16%). Seroprevalence was significantly higher among dogs from families of lower socioeconomic status/level (I, 86%), followed by level II (74%), and III (36%) (p = 0.001). All dogs exhibiting anorexia (12%) were invariably seropositive (100%) (p = 0.029). Seroprevalence was higher among those showing mucocutaneous paleness (95%) compared to those without paleness (68%) (p = 0.013) (OR = 9.3; 95%CI 1.18–72.9). There was high variability in seroprevalence through the studied areas, ranging from 0% (La Libertad Park) up to Combia, Cesar Nader, Las Brisas and Saturno localities (100%) (p = 0.033). Interpretation: Given the high seroprevalence obtained in an area with documented ticks, there is a potential risk of zoonotic transmission to humans. Further seroprevalence studies in humans are needed to assess the prevalence of infections. Poverty is highly associated with these tick-borne pathogens in Pereira, as shown in the present study. |
| first_indexed | 2024-04-14T06:53:40Z |
| format | Article |
| id | doaj.art-bb93942862a64f9fb3b278e356cdbfdf |
| institution | Directory Open Access Journal |
| issn | 2405-6731 |
| language | English |
| last_indexed | 2024-04-14T06:53:40Z |
| publishDate | 2022-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Parasite Epidemiology and Control |
| spelling | doaj.art-bb93942862a64f9fb3b278e356cdbfdf2022-12-22T02:06:57ZengElsevierParasite Epidemiology and Control2405-67312022-05-0117e00249Seroprevalence canine survey for selected vector-borne pathogens and its relationship with poverty in metropolitan Pereira, Colombia, 2020D. Katterine Bonilla-Aldana0Erwin J. Gutiérrez-Grajales1J. Paola Martínez-Arboleda2María Angelica Reina-Mora3Adrián E. Trejos-Mendoza4Soffia Pérez-Vargas5Lorenzo Valencia-Mejía6Luisa F. Marín-Arboleda7Daniela Osorio-Navia8Mariana Chacón-Peña9Luz Victoria González-Colonia10Jaime A. Cardona-Ospina11Erika Vanessa Jiménez-Posada12Andrés Diaz13Jean Carlos Salazar14Manuel Sierra15Fausto Muñoz-Lara16Lysien I. Zambrano17Eduardo Ramírez-Vallejo18Juan Camilo Álvarez19Ingrid Lorena Jaramillo-Delgado20Samuel Pecho-Silva21Alberto Paniz-Mondolfi22Álvaro A. Faccini-Martínez23Alfonso J. Rodríguez-Morales24Semillero de Investigación en Zoonosis (SIZOO), Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia; Institución Universitaria Visión de las Américas, Pereira, Risaralda, Colombia; Red Colombiana de Enfermedades Transmitidas por Garrapatas en Pequeños Animales (RECEPA) – Colombian Network of Tick-Borne Diseases in Small Animals (RECEPA), Pereira, Risaralda, Colombia; Committee of Tropical Medicine, Zoonoses and Travel Medicine, Asociación Colombiana de Infectología, Bogotá, ColombiaRed Colombiana de Enfermedades Transmitidas por Garrapatas en Pequeños Animales (RECEPA) – Colombian Network of Tick-Borne Diseases in Small Animals (RECEPA), Pereira, Risaralda, ColombiaSemillero de Investigación en Zoonosis (SIZOO), Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia; Institución Universitaria Visión de las Américas, Pereira, Risaralda, ColombiaSemillero de Investigación en Zoonosis (SIZOO), Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia; Institución Universitaria Visión de las Américas, Pereira, Risaralda, ColombiaSemillero de Investigación en Zoonosis (SIZOO), Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia; Institución Universitaria Visión de las Américas, Pereira, Risaralda, ColombiaSemillero de Investigación en Zoonosis (SIZOO), Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia; Institución Universitaria Visión de las Américas, Pereira, Risaralda, ColombiaSemillero de Investigación en Zoonosis (SIZOO), Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia; Institución Universitaria Visión de las Américas, Pereira, Risaralda, ColombiaSemillero de Investigación en Zoonosis (SIZOO), Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia; Institución Universitaria Visión de las Américas, Pereira, Risaralda, ColombiaSemillero de Investigación en Zoonosis (SIZOO), Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia; Institución Universitaria Visión de las Américas, Pereira, Risaralda, ColombiaSemillero de Investigación en Zoonosis (SIZOO), Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia; Institución Universitaria Visión de las Américas, Pereira, Risaralda, ColombiaSan Lucas Centro Veterinario y Diagnóstico, Pereira, Risaralda, ColombiaInstitución Universitaria Visión de las Américas, Pereira, Risaralda, Colombia; Grupo de Investigación Biomedicina, Faculty of Medicine, Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia; Grupo de Investigación en Infecciones Emergentes y Medicina Tropical, Instituto para la Investigación en Ciencias Biomédicas, SCI-HELP, Pereira, Risaralda, Colombia; Committee of Tropical Medicine, Zoonoses and Travel Medicine, Asociación Colombiana de Infectología, Bogotá, ColombiaGrupo de Investigación en Infecciones Emergentes y Medicina Tropical, Instituto para la Investigación en Ciencias Biomédicas, SCI-HELP, Pereira, Risaralda, ColombiaVitalcare, Armenia, Quindío, ColombiaVitalcare, Armenia, Quindío, ColombiaUnit of Scientific Research, School of Medical, Faculty of Medical Sciences, Universidad Nacional Autónoma de Honduras (UNAH), Tegucigalpa, HondurasDepartment of Internal Medicine, Faculty of Medical Sciences, Universidad Nacional Autónoma de Honduras (UNAH), Tegucigalpa, Honduras; Department of Internal Medicine, Hospital Escuela, Tegucigalpa, HondurasUnit of Scientific Research, School of Medical, Faculty of Medical Sciences, Universidad Nacional Autónoma de Honduras (UNAH), Tegucigalpa, HondurasIPS Cardiológica Eduardo Ramírez, Pereira, Risaralda, ColombiaGrupo de Investigación One-Health, Departamento de Investigación de Enfermedades Infecciosas en Animales, Centro de Diagnóstico Especializado Testmol, Medellín, Antioquia, ColombiaRed Colombiana de Enfermedades Transmitidas por Garrapatas en Pequeños Animales (RECEPA) – Colombian Network of Tick-Borne Diseases in Small Animals (RECEPA), Pereira, Risaralda, Colombia; Grupo de Investigación One-Health, Departamento de Investigación de Enfermedades Infecciosas en Animales, Centro de Diagnóstico Especializado Testmol, Medellín, Antioquia, ColombiaUniversidad Cientifica del Sur, Lima, Peru; Hospital Nacional Edgardo Rebagliati Martins, Lima, PeruLaboratory of Medical Microbiology, Department of Pathology, Molecular and Cell-based Medicine, The Mount Sinai Hospital-Icahn School of Medicine at Mount Sinai, New York, USARed Colombiana de Enfermedades Transmitidas por Garrapatas en Pequeños Animales (RECEPA) – Colombian Network of Tick-Borne Diseases in Small Animals (RECEPA), Pereira, Risaralda, Colombia; Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA; Committee of Tropical Medicine, Zoonoses and Travel Medicine, Asociación Colombiana de Infectología, Bogotá, ColombiaInstitución Universitaria Visión de las Américas, Pereira, Risaralda, Colombia; Red Colombiana de Enfermedades Transmitidas por Garrapatas en Pequeños Animales (RECEPA) – Colombian Network of Tick-Borne Diseases in Small Animals (RECEPA), Pereira, Risaralda, Colombia; Grupo de Investigación Biomedicina, Faculty of Medicine, Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia; Grupo de Investigación en Infecciones Emergentes y Medicina Tropical, Instituto para la Investigación en Ciencias Biomédicas, SCI-HELP, Pereira, Risaralda, Colombia; Universidad Cientifica del Sur, Lima, Peru; Committee of Tropical Medicine, Zoonoses and Travel Medicine, Asociación Colombiana de Infectología, Bogotá, Colombia; Corresponding author at: Institución Universitaria Visión de las Américas, Pereira, Risaralda, Colombia.Background: Tick-borne diseases (TBD) and dirofilariosis are currently not under surveillance in most Latin American countries. In addition, there is a significant lack of studies describing the current situation in most endemic areas, including Colombia. Therefore, seroprevalence studies are crucial for understanding the epidemiology of these vector-borne diseases. Methods: A serosurvey for TBD and dirofilariosis among 100 dogs was carried out in the municipality of Pereira, located in the Coffee-Triangle region, Colombia. Samples were tested using a rapid assay test system (SNAP® 4Dx®); based on an enzyme immunoassay technique‚ screening for antibodies to Anaplasma phagocytophilum/platys (sensitivity 99.1%)‚ Borrelia burgdorferi s.l. (98.8%), and Ehrlichia canis/ewingii (96.2%) by using specific antigens and checking for Dirofilaria immitis antigen based on specific antibodies (99.2%). Bivariate analyses were performed on Stata®14, significant p < 0.05. Findings: Global seroprevalence to the selected vector-borne pathogens was 74% (95%CI 65–83%). The highest seroprevalence was found for E. canis/ewingii (74%), followed by A. phagocytophilum/platys (16%). Seropositivity for Borrelia spp. and Dirofilaria spp. was 0%. All Anaplasma spp. seropositive dogs showed co-detection of Ehrlichia spp. (16%). Seroprevalence was significantly higher among dogs from families of lower socioeconomic status/level (I, 86%), followed by level II (74%), and III (36%) (p = 0.001). All dogs exhibiting anorexia (12%) were invariably seropositive (100%) (p = 0.029). Seroprevalence was higher among those showing mucocutaneous paleness (95%) compared to those without paleness (68%) (p = 0.013) (OR = 9.3; 95%CI 1.18–72.9). There was high variability in seroprevalence through the studied areas, ranging from 0% (La Libertad Park) up to Combia, Cesar Nader, Las Brisas and Saturno localities (100%) (p = 0.033). Interpretation: Given the high seroprevalence obtained in an area with documented ticks, there is a potential risk of zoonotic transmission to humans. Further seroprevalence studies in humans are needed to assess the prevalence of infections. Poverty is highly associated with these tick-borne pathogens in Pereira, as shown in the present study.http://www.sciencedirect.com/science/article/pii/S2405673122000137Anaplasma phagocytophilumAnaplasma platysEhrlichia canisEhrlichia ewingiiDirofilaria immitisTick-borne diseases |
| spellingShingle | D. Katterine Bonilla-Aldana Erwin J. Gutiérrez-Grajales J. Paola Martínez-Arboleda María Angelica Reina-Mora Adrián E. Trejos-Mendoza Soffia Pérez-Vargas Lorenzo Valencia-Mejía Luisa F. Marín-Arboleda Daniela Osorio-Navia Mariana Chacón-Peña Luz Victoria González-Colonia Jaime A. Cardona-Ospina Erika Vanessa Jiménez-Posada Andrés Diaz Jean Carlos Salazar Manuel Sierra Fausto Muñoz-Lara Lysien I. Zambrano Eduardo Ramírez-Vallejo Juan Camilo Álvarez Ingrid Lorena Jaramillo-Delgado Samuel Pecho-Silva Alberto Paniz-Mondolfi Álvaro A. Faccini-Martínez Alfonso J. Rodríguez-Morales Seroprevalence canine survey for selected vector-borne pathogens and its relationship with poverty in metropolitan Pereira, Colombia, 2020 Parasite Epidemiology and Control Anaplasma phagocytophilum Anaplasma platys Ehrlichia canis Ehrlichia ewingii Dirofilaria immitis Tick-borne diseases |
| title | Seroprevalence canine survey for selected vector-borne pathogens and its relationship with poverty in metropolitan Pereira, Colombia, 2020 |
| title_full | Seroprevalence canine survey for selected vector-borne pathogens and its relationship with poverty in metropolitan Pereira, Colombia, 2020 |
| title_fullStr | Seroprevalence canine survey for selected vector-borne pathogens and its relationship with poverty in metropolitan Pereira, Colombia, 2020 |
| title_full_unstemmed | Seroprevalence canine survey for selected vector-borne pathogens and its relationship with poverty in metropolitan Pereira, Colombia, 2020 |
| title_short | Seroprevalence canine survey for selected vector-borne pathogens and its relationship with poverty in metropolitan Pereira, Colombia, 2020 |
| title_sort | seroprevalence canine survey for selected vector borne pathogens and its relationship with poverty in metropolitan pereira colombia 2020 |
| topic | Anaplasma phagocytophilum Anaplasma platys Ehrlichia canis Ehrlichia ewingii Dirofilaria immitis Tick-borne diseases |
| url | http://www.sciencedirect.com/science/article/pii/S2405673122000137 |
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