Comparative population genetics of the immunity gene, Relish: is adaptive evolution idiosyncratic?
The frequency of adaptive evolution acting on common loci in distant lineages remains an outstanding question in evolutionary biology. We asked whether the immunity factor, Relish, a gene with a history of directional selection in Drosophila simulans, shows evidence of a similar selective history in...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2007-05-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC1859838?pdf=render |
| _version_ | 1818449647758213120 |
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| author | Mia T Levine David J Begun |
| author_facet | Mia T Levine David J Begun |
| author_sort | Mia T Levine |
| collection | DOAJ |
| description | The frequency of adaptive evolution acting on common loci in distant lineages remains an outstanding question in evolutionary biology. We asked whether the immunity factor, Relish, a gene with a history of directional selection in Drosophila simulans, shows evidence of a similar selective history in other Drosophila species. We found only weak evidence of recurrent adaptive protein evolution at the Relish locus in three sister species pairs, suggesting that this key component of the insect immune system has an idiosyncratic evolutionary history in Drosophila. |
| first_indexed | 2024-12-14T20:38:44Z |
| format | Article |
| id | doaj.art-bb93d289fe014812866221d1049853ba |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-14T20:38:44Z |
| publishDate | 2007-05-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-bb93d289fe014812866221d1049853ba2022-12-21T22:48:20ZengPublic Library of Science (PLoS)PLoS ONE1932-62032007-05-0125e44210.1371/journal.pone.0000442Comparative population genetics of the immunity gene, Relish: is adaptive evolution idiosyncratic?Mia T LevineDavid J BegunThe frequency of adaptive evolution acting on common loci in distant lineages remains an outstanding question in evolutionary biology. We asked whether the immunity factor, Relish, a gene with a history of directional selection in Drosophila simulans, shows evidence of a similar selective history in other Drosophila species. We found only weak evidence of recurrent adaptive protein evolution at the Relish locus in three sister species pairs, suggesting that this key component of the insect immune system has an idiosyncratic evolutionary history in Drosophila.http://europepmc.org/articles/PMC1859838?pdf=render |
| spellingShingle | Mia T Levine David J Begun Comparative population genetics of the immunity gene, Relish: is adaptive evolution idiosyncratic? PLoS ONE |
| title | Comparative population genetics of the immunity gene, Relish: is adaptive evolution idiosyncratic? |
| title_full | Comparative population genetics of the immunity gene, Relish: is adaptive evolution idiosyncratic? |
| title_fullStr | Comparative population genetics of the immunity gene, Relish: is adaptive evolution idiosyncratic? |
| title_full_unstemmed | Comparative population genetics of the immunity gene, Relish: is adaptive evolution idiosyncratic? |
| title_short | Comparative population genetics of the immunity gene, Relish: is adaptive evolution idiosyncratic? |
| title_sort | comparative population genetics of the immunity gene relish is adaptive evolution idiosyncratic |
| url | http://europepmc.org/articles/PMC1859838?pdf=render |
| work_keys_str_mv | AT miatlevine comparativepopulationgeneticsoftheimmunitygenerelishisadaptiveevolutionidiosyncratic AT davidjbegun comparativepopulationgeneticsoftheimmunitygenerelishisadaptiveevolutionidiosyncratic |