Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation
Background Ascending/descending myelomalacia (ADMM) is a severe complication of thoracolumbar intervertebral disk herniation (TL‐IVDH) in dogs. Hypothesis/Objectives To investigate the prevalence and risk factors for ADMM in nonambulatory dogs with surgically treated TL‐IVDH. Animals Six‐hundred and...
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| Format: | Article |
| Language: | English |
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Wiley
2017-03-01
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| Series: | Journal of Veterinary Internal Medicine |
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| Online Access: | https://doi.org/10.1111/jvim.14656 |
| _version_ | 1828142064429170688 |
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| author | F. Balducci S. Canal B. Contiero M. Bernardini |
| author_facet | F. Balducci S. Canal B. Contiero M. Bernardini |
| author_sort | F. Balducci |
| collection | DOAJ |
| description | Background Ascending/descending myelomalacia (ADMM) is a severe complication of thoracolumbar intervertebral disk herniation (TL‐IVDH) in dogs. Hypothesis/Objectives To investigate the prevalence and risk factors for ADMM in nonambulatory dogs with surgically treated TL‐IVDH. Animals Six‐hundred and fifty‐two client‐owned dogs evaluated for TL‐IVDH that underwent decompressive spinal surgery. Methods Retrospective medical record review from February 2007 through December 2015. Results Thirteen dogs developed ADMM, with an overall prevalence of 2.0%. The prevalence of ADMM was 0% in dogs with neurological signs graded 1 or 2 at admission or before magnetic resonance imaging (MRI) or surgical procedures, 0.6% in dogs with neurological signs graded 3, 2.7% in dogs with neurological signs graded 4, and 14.5% in dogs with neurological signs graded 5. Age (<5.8 years), neurological status (grade 5), site of disk herniation (L5‐L6), duration of clinical signs before becoming nonambulatory (<24 hours), detection of intramedullary T2‐weighted (T2W) hyperintensity, and a T2 length ratio >4.57 were significant risk factors in the univariate analysis for development of ADMM. Conclusions and Clinical Importance The factors identified in this study may be useful for the prediction of ADMM. Multicenter studies with a higher number of dogs with ADMM are required to confirm these data. |
| first_indexed | 2024-04-11T19:35:27Z |
| format | Article |
| id | doaj.art-bb9514cbe1fb409fb91bda0bc1ce3eea |
| institution | Directory Open Access Journal |
| issn | 0891-6640 1939-1676 |
| language | English |
| last_indexed | 2024-04-11T19:35:27Z |
| publishDate | 2017-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Veterinary Internal Medicine |
| spelling | doaj.art-bb9514cbe1fb409fb91bda0bc1ce3eea2022-12-22T04:06:53ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762017-03-0131249850410.1111/jvim.14656Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk HerniationF. Balducci0S. Canal1B. Contiero2M. Bernardini3Neurology Unit Portoni Rossi Veterinary Hospital Zola Predosa Bologna ItalyNeurology Unit Portoni Rossi Veterinary Hospital Zola Predosa Bologna ItalyDepartment of Animal Medicine, Production and Health Clinical Section University of Padua Legnaro Padua ItalyNeurology Unit Portoni Rossi Veterinary Hospital Zola Predosa Bologna ItalyBackground Ascending/descending myelomalacia (ADMM) is a severe complication of thoracolumbar intervertebral disk herniation (TL‐IVDH) in dogs. Hypothesis/Objectives To investigate the prevalence and risk factors for ADMM in nonambulatory dogs with surgically treated TL‐IVDH. Animals Six‐hundred and fifty‐two client‐owned dogs evaluated for TL‐IVDH that underwent decompressive spinal surgery. Methods Retrospective medical record review from February 2007 through December 2015. Results Thirteen dogs developed ADMM, with an overall prevalence of 2.0%. The prevalence of ADMM was 0% in dogs with neurological signs graded 1 or 2 at admission or before magnetic resonance imaging (MRI) or surgical procedures, 0.6% in dogs with neurological signs graded 3, 2.7% in dogs with neurological signs graded 4, and 14.5% in dogs with neurological signs graded 5. Age (<5.8 years), neurological status (grade 5), site of disk herniation (L5‐L6), duration of clinical signs before becoming nonambulatory (<24 hours), detection of intramedullary T2‐weighted (T2W) hyperintensity, and a T2 length ratio >4.57 were significant risk factors in the univariate analysis for development of ADMM. Conclusions and Clinical Importance The factors identified in this study may be useful for the prediction of ADMM. Multicenter studies with a higher number of dogs with ADMM are required to confirm these data.https://doi.org/10.1111/jvim.14656CanineContusive injuryDeep pain perceptionSpinal cord injury |
| spellingShingle | F. Balducci S. Canal B. Contiero M. Bernardini Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation Journal of Veterinary Internal Medicine Canine Contusive injury Deep pain perception Spinal cord injury |
| title | Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation |
| title_full | Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation |
| title_fullStr | Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation |
| title_full_unstemmed | Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation |
| title_short | Prevalence and Risk Factors for Presumptive Ascending/Descending Myelomalacia in Dogs after Thoracolumbar Intervertebral Disk Herniation |
| title_sort | prevalence and risk factors for presumptive ascending descending myelomalacia in dogs after thoracolumbar intervertebral disk herniation |
| topic | Canine Contusive injury Deep pain perception Spinal cord injury |
| url | https://doi.org/10.1111/jvim.14656 |
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