Thrombocytopenia and Coronary Artery Disease, the Existing Dilemmas

Background: Platelets play a pivotal role in the pathogenesis of acute coronary syndrome (ACS) and acute or chronic complications following percutaneous coronary intervention (PCI) as well. Platelet inhibition is a cornerstone treatment in the management of these patients. Thrombocytopenia in patien...

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Bibliographic Details
Main Authors: Davarashvili Ilia, Hasin Tal, Asher Elad
Format: Article
Language:English
Published: Sciendo 2019-09-01
Series:Journal of Cardiovascular Emergencies
Subjects:
Online Access:https://doi.org/10.2478/jce-2019-0011
Description
Summary:Background: Platelets play a pivotal role in the pathogenesis of acute coronary syndrome (ACS) and acute or chronic complications following percutaneous coronary intervention (PCI) as well. Platelet inhibition is a cornerstone treatment in the management of these patients. Thrombocytopenia in patients with ACS is uncommon. Idiopathic thrombocytopenic purpura (ITP) is a rare phenomenon; nevertheless, some case series presenting concomitant ACS and ITP have been described in the literature. The safety of antiplatelet therapy and PCI in patients who have ACS and thrombocytopenia is limited.
ISSN:2457-5518