The Landscape and Therapeutic Implications of Molecular Profiles in Epithelial Ovarian Cancer
Epithelial ovarian cancer (EOC) affects 43,000 women worldwide every year and has a five-year survival rate of 30%. Mainstay treatment is extensive surgery and chemotherapy. Outcomes could be improved by molecular profiling. We conducted a review of the literature to identify relevant publications o...
Main Authors: | Ludivine Dion, Isis Carton, Sylvie Jaillard, Krystel Nyangoh Timoh, Sébastien Henno, Hugo Sardain, Fabrice Foucher, Jean Levêque, Thibault de la Motte Rouge, Susie Brousse, Vincent Lavoué |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-07-01
|
Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0383/9/7/2239 |
Similar Items
-
Abrogation of KLF5 sensitizes BRCA1-proficient pancreatic cancer to PARP inhibition
by: Zhang Zheng, et al.
Published: (2024-03-01) -
Targeting the DNA repair pathway for breast cancer therapy: Beyond the molecular subtypes
by: Yuting Qu, et al.
Published: (2023-12-01) -
Biomarkers for Homologous Recombination Deficiency in Cancer
by: Svenja Wagener-Ryczek, et al.
Published: (2021-06-01) -
Pharmacologic Induction of BRCAness in <i>BRCA</i>-Proficient Cancers: Expanding PARP Inhibitor Use
by: Rachel Abbotts, et al.
Published: (2022-05-01) -
How BRCA and homologous recombination deficiency change therapeutic strategies in ovarian cancer: a review of literature
by: Martina Arcieri, et al.
Published: (2024-03-01)