Candida Antifungal Resistance and Therapeutic Approach
Species from genus Candida are characterized by their opportunistic nature and can trigger several infections, especially in immunocompromised hosts. The emergence of non-albicans Candida species, associated with high morbidity and mortality rates, is largely associated with the mechanisms of resis...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Formifarma, LDA.
2017-08-01
|
| Series: | Revista Portuguesa de Farmacoterapia |
| Subjects: | |
| Online Access: | http://farmacoterapia.pt/index.php/rpf/article/view/158 |
| _version_ | 1797730069254242304 |
|---|---|
| author | Francisca Vieira Teresa Nascimento |
| author_facet | Francisca Vieira Teresa Nascimento |
| author_sort | Francisca Vieira |
| collection | DOAJ |
| description |
Species from genus Candida are characterized by their opportunistic nature and can trigger several infections, especially in immunocompromised hosts. The emergence of non-albicans Candida species, associated with high morbidity and mortality rates, is largely associated with the mechanisms of resistance, intrinsic or acquired, to the conventionally antifungal agents used. Their understanding is fundamental for the development of effective therapeutic approaches. The diagnosis and treatment of these infections poses to be a real challenge and treatment should be implemented as soon as possible. However, on one hand the empirical use of antifungal agents correlates with increased resistance of non-albicans Candida species, on the other hand the antifungal susceptibility testing acts as an auxiliary for targeted therapy, and it is implicit a reduction in the development of resistant species.
|
| first_indexed | 2024-03-12T11:38:50Z |
| format | Article |
| id | doaj.art-bb986e0b44af4c86be9e4cb68d84d9b5 |
| institution | Directory Open Access Journal |
| issn | 1647-354X 2183-7341 |
| language | English |
| last_indexed | 2024-03-12T11:38:50Z |
| publishDate | 2017-08-01 |
| publisher | Formifarma, LDA. |
| record_format | Article |
| series | Revista Portuguesa de Farmacoterapia |
| spelling | doaj.art-bb986e0b44af4c86be9e4cb68d84d9b52023-08-31T22:40:44ZengFormifarma, LDA.Revista Portuguesa de Farmacoterapia1647-354X2183-73412017-08-019310.25756/rpf.v9i3.158Candida Antifungal Resistance and Therapeutic ApproachFrancisca Vieira0Teresa Nascimento1Instituto Superior de Ciências da Saúde Egas Moniz, Campus Universitário - Quinta da Granja - Monte de Caparica 2829-511 Caparica, PortugalInstituto Superior de Ciências da Saúde Egas Moniz (ISCSEM), Caparica, Portugal Centro de investigação interdisciplinar Egas Moniz (CiiEM), Caparica, Portugal Species from genus Candida are characterized by their opportunistic nature and can trigger several infections, especially in immunocompromised hosts. The emergence of non-albicans Candida species, associated with high morbidity and mortality rates, is largely associated with the mechanisms of resistance, intrinsic or acquired, to the conventionally antifungal agents used. Their understanding is fundamental for the development of effective therapeutic approaches. The diagnosis and treatment of these infections poses to be a real challenge and treatment should be implemented as soon as possible. However, on one hand the empirical use of antifungal agents correlates with increased resistance of non-albicans Candida species, on the other hand the antifungal susceptibility testing acts as an auxiliary for targeted therapy, and it is implicit a reduction in the development of resistant species. http://farmacoterapia.pt/index.php/rpf/article/view/158Antifungal Agents/therapeutic useCandidaDrug ResistanceFungalInvasive Fungal Infections |
| spellingShingle | Francisca Vieira Teresa Nascimento Candida Antifungal Resistance and Therapeutic Approach Revista Portuguesa de Farmacoterapia Antifungal Agents/therapeutic use Candida Drug Resistance Fungal Invasive Fungal Infections |
| title | Candida Antifungal Resistance and Therapeutic Approach |
| title_full | Candida Antifungal Resistance and Therapeutic Approach |
| title_fullStr | Candida Antifungal Resistance and Therapeutic Approach |
| title_full_unstemmed | Candida Antifungal Resistance and Therapeutic Approach |
| title_short | Candida Antifungal Resistance and Therapeutic Approach |
| title_sort | candida antifungal resistance and therapeutic approach |
| topic | Antifungal Agents/therapeutic use Candida Drug Resistance Fungal Invasive Fungal Infections |
| url | http://farmacoterapia.pt/index.php/rpf/article/view/158 |
| work_keys_str_mv | AT franciscavieira candidaantifungalresistanceandtherapeuticapproach AT teresanascimento candidaantifungalresistanceandtherapeuticapproach |