Infection with a Nonencapsulated <i>Bacillus anthracis</i> Strain in Rabbits—The Role of Bacterial Adhesion and the Potential for a Safe Live Attenuated Vaccine

Infection with a Nonencapsulated <i>Bacillus anthracis</i> Strain in Rabbits—The Role of Bacterial Adhesion and the Potential for a Safe Live Attenuated Vaccine

Nonencapsulated (∆pXO2) <i>Bacillus anthracis</i> strains are commonly used as vaccines and for anthrax research, mainly in the mouse model. Previously, we demonstrated that the infection of rabbits, intranasally or subcutaneously, with the spores of a fully virulent strain results in th...

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Bibliographic Details
Main Authors: Itai Glinert, Shay Weiss, Assa Sittner, Elad Bar-David, Amir Ben-Shmuel, Josef Schlomovitz, David Kobiler, Haim Levy
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Toxins
Subjects:
<i>Bacillus anthacis</i>
vaccine strain
BslA
cell adherence
encephalitis
CNS infection
Online Access:https://www.mdpi.com/2072-6651/10/12/506

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