Analysis of peripapillary choroidal thickness in unilateral amblyopia
Purpose: To evaluate the peripapillary choroidal thickness (CT) in children with unilateral amblyopia using spectral-domain optical coherence tomography (SD-OCT). Methods: One hundred and six eyes of 53 children with unilateral amblyopia and 20 eyes of 20 children with normal vision were involved i...
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| Format: | Article |
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Knowledge E
2019-01-01
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| Series: | Journal of Ophthalmic & Vision Research |
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| Online Access: | http://www.jovr.org/article.asp?issn=2008-322X;year=2019;volume=14;issue=1;spage=42;epage=47;aulast=Bitirgen |
| _version_ | 1811249628759195648 |
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| author | Gulfidan Bitirgen Enver Mirza Ahmet Ozkagnici Mehmet Sinan Iyisoy |
| author_facet | Gulfidan Bitirgen Enver Mirza Ahmet Ozkagnici Mehmet Sinan Iyisoy |
| author_sort | Gulfidan Bitirgen |
| collection | DOAJ |
| description | Purpose: To evaluate the peripapillary choroidal thickness (CT) in children with unilateral amblyopia using spectral-domain optical coherence tomography (SD-OCT).
Methods: One hundred and six eyes of 53 children with unilateral amblyopia and 20 eyes of 20 children with normal vision were involved in this study. Of the 53 children with unilateral amblyopia, 29 (54.7%) had hyperopic anisometropic amblyopia and 24 (45.3%) had strabismic amblyopia. Peripapillary CT was measured from 6 mm length radial B-scans at the optic nerve head using the enhanced depth imaging program of an SD-OCT (Heidelberg Engineering, Germany). Age, sex, refractive error, and best-corrected visual acuity were also recorded.
Results: The average peripapillary CT was greater in amblyopic eyes than in the fellow eyes of the children with amblyopia (P = 0.002), and control eyes (P < 0.001). There was no significant difference between the fellow eyes of children with amblyopia and the control eyes (P = 0.158). The average peripapillary CT was negatively correlated with axial length (AL) in amblyopic eyes (r = -0.381; P = 0.005) and fellow eyes (r = -0.392; P = 0.004) but not in control eyes (r = -0.232; P = 0.325). After adjustment for the possible effects of AL, the average peripapillary CT in amblyopic eyes was still greater than in fellow eyes (P = 0.014) and control eyes (P = 0.022).
Conclusion: The peripapillary choroid of eyes with amblyopia was thicker than that of the fellow eyes and control eyes. No significant difference was observed between fellow eyes and control eyes. |
| first_indexed | 2024-04-12T15:50:01Z |
| format | Article |
| id | doaj.art-bb9afbfa3a3d4f04bf29ad8345530bad |
| institution | Directory Open Access Journal |
| issn | 2008-322X |
| language | English |
| last_indexed | 2024-04-12T15:50:01Z |
| publishDate | 2019-01-01 |
| publisher | Knowledge E |
| record_format | Article |
| series | Journal of Ophthalmic & Vision Research |
| spelling | doaj.art-bb9afbfa3a3d4f04bf29ad8345530bad2022-12-22T03:26:32ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2019-01-01141424710.4103/jovr.jovr_141_17Analysis of peripapillary choroidal thickness in unilateral amblyopiaGulfidan BitirgenEnver MirzaAhmet OzkagniciMehmet Sinan IyisoyPurpose: To evaluate the peripapillary choroidal thickness (CT) in children with unilateral amblyopia using spectral-domain optical coherence tomography (SD-OCT). Methods: One hundred and six eyes of 53 children with unilateral amblyopia and 20 eyes of 20 children with normal vision were involved in this study. Of the 53 children with unilateral amblyopia, 29 (54.7%) had hyperopic anisometropic amblyopia and 24 (45.3%) had strabismic amblyopia. Peripapillary CT was measured from 6 mm length radial B-scans at the optic nerve head using the enhanced depth imaging program of an SD-OCT (Heidelberg Engineering, Germany). Age, sex, refractive error, and best-corrected visual acuity were also recorded. Results: The average peripapillary CT was greater in amblyopic eyes than in the fellow eyes of the children with amblyopia (P = 0.002), and control eyes (P < 0.001). There was no significant difference between the fellow eyes of children with amblyopia and the control eyes (P = 0.158). The average peripapillary CT was negatively correlated with axial length (AL) in amblyopic eyes (r = -0.381; P = 0.005) and fellow eyes (r = -0.392; P = 0.004) but not in control eyes (r = -0.232; P = 0.325). After adjustment for the possible effects of AL, the average peripapillary CT in amblyopic eyes was still greater than in fellow eyes (P = 0.014) and control eyes (P = 0.022). Conclusion: The peripapillary choroid of eyes with amblyopia was thicker than that of the fellow eyes and control eyes. No significant difference was observed between fellow eyes and control eyes.http://www.jovr.org/article.asp?issn=2008-322X;year=2019;volume=14;issue=1;spage=42;epage=47;aulast=BitirgenAmblyopia; Anisometropia; Optical Coherence Tomography; Peripapillary Choroidal Thickness; Strabismus |
| spellingShingle | Gulfidan Bitirgen Enver Mirza Ahmet Ozkagnici Mehmet Sinan Iyisoy Analysis of peripapillary choroidal thickness in unilateral amblyopia Journal of Ophthalmic & Vision Research Amblyopia; Anisometropia; Optical Coherence Tomography; Peripapillary Choroidal Thickness; Strabismus |
| title | Analysis of peripapillary choroidal thickness in unilateral amblyopia |
| title_full | Analysis of peripapillary choroidal thickness in unilateral amblyopia |
| title_fullStr | Analysis of peripapillary choroidal thickness in unilateral amblyopia |
| title_full_unstemmed | Analysis of peripapillary choroidal thickness in unilateral amblyopia |
| title_short | Analysis of peripapillary choroidal thickness in unilateral amblyopia |
| title_sort | analysis of peripapillary choroidal thickness in unilateral amblyopia |
| topic | Amblyopia; Anisometropia; Optical Coherence Tomography; Peripapillary Choroidal Thickness; Strabismus |
| url | http://www.jovr.org/article.asp?issn=2008-322X;year=2019;volume=14;issue=1;spage=42;epage=47;aulast=Bitirgen |
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