Prostate Cancer Tumor Stroma: Responsibility in Tumor Biology, Diagnosis and Treatment

Prostate Cancer Tumor Stroma: Responsibility in Tumor Biology, Diagnosis and Treatment

Prostate cancer (PCa) is a common cancer among males globally, and its occurrence is growing worldwide. Clinical decisions about the combination of therapies are becoming highly relevant. However, this is a heterogeneous disease, ranging widely in prognosis. Therefore, new approaches are needed base...

Full description

Bibliographic Details
Main Authors:	Luis O. González, Noemi Eiro, Maria Fraile, Nana Beridze, Andres R. Escaf, Safwan Escaf, Jesús M. Fernández-Gómez, Francisco J. Vizoso
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Series:	Cancers
Subjects:	cancer-associated fibroblasts mesenchymal stromal cells tumor microenvironment extracellular vesicles exosomes biochemical recurrence in prostate cancer
Online Access:	https://www.mdpi.com/2072-6694/14/18/4412

Similar Items

The Coronavirus Pandemic (SARS-CoV-2): New Problems Demand New Solutions, the Alternative of Mesenchymal (Stem) Stromal Cells
by: Noemi Eiro, et al.
Published: (2020-07-01)

Targeting the tumor stroma for cancer therapy
by: Maosen Xu, et al.
Published: (2022-11-01)

Breast Cancer Tumor Stroma: Cellular Components, Phenotypic Heterogeneity, Intercellular Communication, Prognostic Implications and Therapeutic Opportunities
by: Noemi Eiro, et al.
Published: (2019-05-01)

Extracellular Vesicles in Prostate Cancer Carcinogenesis, Diagnosis, and Management
by: Virginie Vlaeminck-Guillem, et al.
Published: (2018-06-01)

Potential Roles of Tumor Cell- and Stroma Cell-Derived Small Extracellular Vesicles in Promoting a Pro-Angiogenic Tumor Microenvironment
by: Nils Ludwig, et al.
Published: (2020-12-01)

Low Tumor-to-Stroma Ratio Reflects Protective Role of Stroma against Prostate Cancer Progression
by: Paulina Nastały, et al.
Published: (2021-10-01)

Mesenchymal Stem/Stromal Cells and Their Derivates in Acute Diseases: Emergency in the Post-COVID-19 Times
by: Francisco J. Vizoso, et al.
Published: (2021-08-01)

Protein cargo in extracellular vesicles as the key mediator in the progression of cancer
by: Klára Hánělová, et al.
Published: (2024-01-01)

Gene Expression Profile of Stromal Factors in Cancer-Associated Fibroblasts from Prostate Cancer
by: Noemi Eiro, et al.
Published: (2022-06-01)

In-Depth Characterization of Stromal Cells within the Tumor Microenvironment Yields Novel Therapeutic Targets
by: Sebastian G. Walter, et al.
Published: (2021-03-01)

The Emerging Roles of Extracellular Vesicles As Communication Vehicles within the Tumor Microenvironment and Beyond
by: Ryan Sullivan, et al.
Published: (2017-08-01)

Evaluation of Matrix Metalloproteases by Artificial Intelligence Techniques in Negative Biopsies as New Diagnostic Strategy in Prostate Cancer
by: Noemi Eiro, et al.
Published: (2023-04-01)

Nanomedicine Strategies for Targeting Tumor Stroma
by: Mei-Chi Su, et al.
Published: (2023-08-01)

Crosstalk Between Mesenchymal Stromal Cells and Tumor-Associated Macrophages in Gastric Cancer
by: Ping Zheng, et al.
Published: (2020-10-01)

Role of Exosomes in Prostate Cancer Metastasis
by: Theresa Akoto, et al.
Published: (2021-03-01)

A Five Glutamine-Associated Signature Predicts Prognosis of Prostate Cancer and Links Glutamine Metabolism with Tumor Microenvironment
by: Hai Wang, et al.
Published: (2023-03-01)

Extracellular Vesicles as a Translational Approach for the Treatment of COVID-19 Disease: An Updated Overview
by: Enrica Serretiello, et al.
Published: (2023-09-01)

Offsetting Expression Profiles of Prognostic Markers in Prostate Tumor vs. Its Microenvironment
by: Zhenyu Jia, et al.
Published: (2019-06-01)

The Influence of a Stressful Microenvironment on Tumor Exosomes: A Focus on the DNA Cargo
by: Rossana Domenis, et al.
Published: (2020-11-01)

A Gene Prognostic Index Associated With Epithelial-Mesenchymal Transition Predicting Biochemical Recurrence and Tumor Chemoresistance for Prostate Cancer
by: Dechao Feng, et al.
Published: (2022-01-01)

Stroma‐derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer
by: Alex P. Shephard, et al.
Published: (2021-10-01)

Extracellular vesicle-orchestrated crosstalk between cancer-associated fibroblasts and tumors
by: Chuanshi He, et al.
Published: (2021-12-01)

Dynamic Stromal Alterations Influence Tumor-Stroma Crosstalk to Promote Pancreatic Cancer and Treatment Resistance
by: Kendelle J. Murphy, et al.
Published: (2021-07-01)

Metabolic syndrome-related prognostic index: Predicting biochemical recurrence and differentiating between cold and hot tumors in prostate cancer
by: Congzhe Ren, et al.
Published: (2023-03-01)

A Novel Ferroptosis-Based Molecular Signature Associated with Biochemical Recurrence-Free Survival and Tumor Immune Microenvironment of Prostate Cancer
by: Zhi-Bin Ke, et al.
Published: (2022-01-01)

Strategies for Efficient Targeting of Tumor Collagen for Cancer Therapy
by: Silvia Baldari, et al.
Published: (2022-09-01)

The emerging role of exosomes in Epithelial-Mesenchymal-Transition in cancer.
by: Laura Jayne Vella
Published: (2014-12-01)

Exosomes in Prostate Cancer: Putting Together the Pieces of a Puzzle
by: Colleen C. Nelson, et al.
Published: (2013-11-01)

Immunophenotype Rearrangement in Response to Tumor Excision May Be Related to the Risk of Biochemical Recurrence in Prostate Cancer Patients
by: Paulius Bosas, et al.
Published: (2021-08-01)

Proteomic Analyses of Fibroblast- and Serum-Derived Exosomes Identify QSOX1 as a Marker for Non-invasive Detection of Colorectal Cancer
by: Nicole Ganig, et al.
Published: (2021-03-01)

Prognostic Significance of Gene Expression and DNA Methylation Markers in Circulating Tumor Cells and Paired Plasma Derived Exosomes in Metastatic Castration Resistant Prostate Cancer
by: Martha Zavridou, et al.
Published: (2021-02-01)

Tumor immune contexture predicts recurrence after prostatectomy and efficacy of androgen deprivation and immunotherapy in prostate cancer
by: Sujun Han, et al.
Published: (2023-03-01)

Extracellular Vesicles: Messengers of p53 in Tumor–Stroma Communication and Cancer Metastasis
by: Evangelos Pavlakis, et al.
Published: (2020-12-01)

Mast Cell-Derived SAMD14 Is a Novel Regulator of the Human Prostate Tumor Microenvironment
by: Linda K. H. Teng, et al.
Published: (2021-03-01)

The Role of Extracellular Vesicles in Metabolic Reprogramming of the Tumor Microenvironment
by: Eran S. Fridman, et al.
Published: (2022-04-01)

Exosome-Based Cell-Cell Communication in the Tumor Microenvironment
by: Joana Maia, et al.
Published: (2018-02-01)

Regulation of Antitumor Immune Responses by Exosomes Derived from Tumor and Immune Cells
by: Andrés Rincón-Riveros, et al.
Published: (2021-02-01)

Prostate Cancer Development Is Not Affected by Statin Use in Patients with Elevated PSA Levels
by: Dennie Meijer, et al.
Published: (2019-07-01)

Development of a novel prostate Cancer-Stroma Sphere (CSS) model for In Vitro tumor microenvironment studies
by: Aigul R. Rakhmatullina, et al.
Published: (2024-06-01)

Adult Stem Cell-Derived Extracellular Vesicles in Cancer Treatment: Opportunities and Challenges
by: Vadims Parfejevs, et al.
Published: (2020-05-01)