Position of oral cephalosporins and its fixed-dose combinations in the guideline recommendations for the management of community-acquired infections
Community-acquired infections (CAIs) represent a major burden for health-care system. This directly aids the emergence of antibiotic-resistant organisms. India is not immune to it. This review assessed the current guideline recommendations for the usage of oral cephalosporins in the management of co...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2023-09-01
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| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/54674 |
| _version_ | 1797721445276581888 |
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| author | Mala Kaneria Ilambarathi M Vishal Singh Varun N Rashmi Hegde Praveen Kamble Krunal Dalal |
| author_facet | Mala Kaneria Ilambarathi M Vishal Singh Varun N Rashmi Hegde Praveen Kamble Krunal Dalal |
| author_sort | Mala Kaneria |
| collection | DOAJ |
| description | Community-acquired infections (CAIs) represent a major burden for health-care system. This directly aids the emergence of antibiotic-resistant organisms. India is not immune to it. This review assessed the current guideline recommendations for the usage of oral cephalosporins in the management of common CAIs. The researchers conducted iterative searches in PubMed, SCOPUS, and Google Scholar for published articles using various keywords. The search was conducted in November 2022 and considered articles published till date. Different CAIs are caused by similar organisms, susceptible to first-line antibiotics such as penicillin and cephalosporins. Most of the guidelines recommend the use of oral cephalosporins for the management of the commonly prevalent CAIs. These antibiotics however should be used as a monotherapy and not as fixed-dose combinations (FDCs), as FDCs with oral cephalosporins lack scientific basis and may be detrimental. For burden of CAIs intensified by anti-microbial resistance, guidelines are useful for the management of CAIs to educate the prescribers and preserve currently available antibiotics. |
| first_indexed | 2024-03-12T09:33:25Z |
| format | Article |
| id | doaj.art-bba01e4975014dd585d55044e9e41e7d |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-03-12T09:33:25Z |
| publishDate | 2023-09-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-bba01e4975014dd585d55044e9e41e7d2023-09-02T13:51:27ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762023-09-01149281291https://doi.org/10.3126/ajms.v14i9.54674Position of oral cephalosporins and its fixed-dose combinations in the guideline recommendations for the management of community-acquired infectionsMala Kaneria 0https://orcid.org/0000-0003-0115-0855Ilambarathi M 1https://orcid.org/0009-0005-2647-003XVishal Singh 2https://orcid.org/0000-0002-5435-8599Varun N 3https://orcid.org/0000-0001-6278-4304Rashmi Hegde4https://orcid.org/0009-0009-9445-0259Praveen Kamble 5https://orcid.org/0000-0002-4082-6101Krunal Dalal 6https://orcid.org/0000-0001-5189-7469Professor and Unit Head, Department of Medicine, Nair Hospital and Consultant in Infectious Diseases and HIV Medicine, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, IndiaConsultant ENT and Plastic Surgeon, Billroth Hospitals, Sundaram Medical Foundation, Railway Hospital, Perambur, Tamil Nadu, India Medical Advisor, Anti-Infectives, GSK, Mumbai, Maharashtra, India Medical Advisor, Anti-Infectives and Dermatology, GSK, Mumbai, Maharashtra, India Executive Vice President - Medical Affairs, GSK, Mumbai, Maharashtra, India Medical Lead - Infectious Disease and Others, Stiefel and Infectious Diseases Medical, GSK, Mumbai, Maharashtra, India Head - Medical Affairs, General Medicine, GSK, Mumbai, Maharashtra, India Community-acquired infections (CAIs) represent a major burden for health-care system. This directly aids the emergence of antibiotic-resistant organisms. India is not immune to it. This review assessed the current guideline recommendations for the usage of oral cephalosporins in the management of common CAIs. The researchers conducted iterative searches in PubMed, SCOPUS, and Google Scholar for published articles using various keywords. The search was conducted in November 2022 and considered articles published till date. Different CAIs are caused by similar organisms, susceptible to first-line antibiotics such as penicillin and cephalosporins. Most of the guidelines recommend the use of oral cephalosporins for the management of the commonly prevalent CAIs. These antibiotics however should be used as a monotherapy and not as fixed-dose combinations (FDCs), as FDCs with oral cephalosporins lack scientific basis and may be detrimental. For burden of CAIs intensified by anti-microbial resistance, guidelines are useful for the management of CAIs to educate the prescribers and preserve currently available antibiotics.https://www.nepjol.info/index.php/AJMS/article/view/54674anti-microbial resistancecephalosporinscommunity-acquired infectionsfixed-dose combinationindia |
| spellingShingle | Mala Kaneria Ilambarathi M Vishal Singh Varun N Rashmi Hegde Praveen Kamble Krunal Dalal Position of oral cephalosporins and its fixed-dose combinations in the guideline recommendations for the management of community-acquired infections Asian Journal of Medical Sciences anti-microbial resistance cephalosporins community-acquired infections fixed-dose combination india |
| title | Position of oral cephalosporins and its fixed-dose combinations in the guideline recommendations for the management of community-acquired infections |
| title_full | Position of oral cephalosporins and its fixed-dose combinations in the guideline recommendations for the management of community-acquired infections |
| title_fullStr | Position of oral cephalosporins and its fixed-dose combinations in the guideline recommendations for the management of community-acquired infections |
| title_full_unstemmed | Position of oral cephalosporins and its fixed-dose combinations in the guideline recommendations for the management of community-acquired infections |
| title_short | Position of oral cephalosporins and its fixed-dose combinations in the guideline recommendations for the management of community-acquired infections |
| title_sort | position of oral cephalosporins and its fixed dose combinations in the guideline recommendations for the management of community acquired infections |
| topic | anti-microbial resistance cephalosporins community-acquired infections fixed-dose combination india |
| url | https://www.nepjol.info/index.php/AJMS/article/view/54674 |
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