Relationship between Biological Markers, Metabolic Components, Lifestyles, and Impaired Fasting Glucose in Male Workers
BackgroundConfirmation regarding the association between impaired fasting glucose (IFG) and biomarkers in addition to metabolic components and lifestyle factors are required in the occupational filed for preventing diabetes mellitus.MethodsThe study was performed in working men aged 30 to 60 years o...
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| Format: | Article |
| Language: | English |
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Korean Diabetes Association
2015-10-01
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| Series: | Diabetes & Metabolism Journal |
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| Online Access: | http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-39-434.pdf |
| _version_ | 1819073217399095296 |
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| author | Tomoyuki Kawada |
| author_facet | Tomoyuki Kawada |
| author_sort | Tomoyuki Kawada |
| collection | DOAJ |
| description | BackgroundConfirmation regarding the association between impaired fasting glucose (IFG) and biomarkers in addition to metabolic components and lifestyle factors are required in the occupational filed for preventing diabetes mellitus.MethodsThe study was performed in working men aged 30 to 60 years old, who were not taking medication for any metabolic diseases. The author measured the serum levels of high-sensitivity C-reactive protein (CRP), uric acid, and plasma fibrinogen as potential biomarkers of IFG.ResultsThe mean serum uric acid, log-transformed serum CRP, and plasma fibrinogen levels were higher in the subjects with IFG than in those without IFG. Multivariate analysis revealed significant associations between the presence of IFG and age, log-transformed value of serum CRP, increased waist circumference, hypertension, and hypertriglyceridemia, with odds ratios of 1.1 (95% confidence interval [CI], 1.08 to 1.1; P<0.001), 1.8 (95% CI, 1.4 to 2.3; P<0.001), 1.3 (95% CI, 1.09 to 1.7; P<0.01), 1.9 (95% CI, 1.6 to 2.3; P<0.001), and 1.3 (95% CI, 1.04 to 1.6; P<0.05), respectively, for the presence of IFG.ConclusionSerum CRP, age, and three metabolic components were associated with IFG. In contrast, there were no significant associations between IFG and lifestyle factors, serum uric acid or plasma fibrinogen. |
| first_indexed | 2024-12-21T17:50:07Z |
| format | Article |
| id | doaj.art-bba599ce586e4babb717f5e8d9af9680 |
| institution | Directory Open Access Journal |
| issn | 2233-6079 2233-6087 |
| language | English |
| last_indexed | 2024-12-21T17:50:07Z |
| publishDate | 2015-10-01 |
| publisher | Korean Diabetes Association |
| record_format | Article |
| series | Diabetes & Metabolism Journal |
| spelling | doaj.art-bba599ce586e4babb717f5e8d9af96802022-12-21T18:55:23ZengKorean Diabetes AssociationDiabetes & Metabolism Journal2233-60792233-60872015-10-0139543443810.4093/dmj.2015.39.5.43414716Relationship between Biological Markers, Metabolic Components, Lifestyles, and Impaired Fasting Glucose in Male WorkersTomoyuki KawadaBackgroundConfirmation regarding the association between impaired fasting glucose (IFG) and biomarkers in addition to metabolic components and lifestyle factors are required in the occupational filed for preventing diabetes mellitus.MethodsThe study was performed in working men aged 30 to 60 years old, who were not taking medication for any metabolic diseases. The author measured the serum levels of high-sensitivity C-reactive protein (CRP), uric acid, and plasma fibrinogen as potential biomarkers of IFG.ResultsThe mean serum uric acid, log-transformed serum CRP, and plasma fibrinogen levels were higher in the subjects with IFG than in those without IFG. Multivariate analysis revealed significant associations between the presence of IFG and age, log-transformed value of serum CRP, increased waist circumference, hypertension, and hypertriglyceridemia, with odds ratios of 1.1 (95% confidence interval [CI], 1.08 to 1.1; P<0.001), 1.8 (95% CI, 1.4 to 2.3; P<0.001), 1.3 (95% CI, 1.09 to 1.7; P<0.01), 1.9 (95% CI, 1.6 to 2.3; P<0.001), and 1.3 (95% CI, 1.04 to 1.6; P<0.05), respectively, for the presence of IFG.ConclusionSerum CRP, age, and three metabolic components were associated with IFG. In contrast, there were no significant associations between IFG and lifestyle factors, serum uric acid or plasma fibrinogen.http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-39-434.pdfC-reactive proteinFibrinogenImpaired fasting glucoseLife styleMetabolic components |
| spellingShingle | Tomoyuki Kawada Relationship between Biological Markers, Metabolic Components, Lifestyles, and Impaired Fasting Glucose in Male Workers Diabetes & Metabolism Journal C-reactive protein Fibrinogen Impaired fasting glucose Life style Metabolic components |
| title | Relationship between Biological Markers, Metabolic Components, Lifestyles, and Impaired Fasting Glucose in Male Workers |
| title_full | Relationship between Biological Markers, Metabolic Components, Lifestyles, and Impaired Fasting Glucose in Male Workers |
| title_fullStr | Relationship between Biological Markers, Metabolic Components, Lifestyles, and Impaired Fasting Glucose in Male Workers |
| title_full_unstemmed | Relationship between Biological Markers, Metabolic Components, Lifestyles, and Impaired Fasting Glucose in Male Workers |
| title_short | Relationship between Biological Markers, Metabolic Components, Lifestyles, and Impaired Fasting Glucose in Male Workers |
| title_sort | relationship between biological markers metabolic components lifestyles and impaired fasting glucose in male workers |
| topic | C-reactive protein Fibrinogen Impaired fasting glucose Life style Metabolic components |
| url | http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-39-434.pdf |
| work_keys_str_mv | AT tomoyukikawada relationshipbetweenbiologicalmarkersmetaboliccomponentslifestylesandimpairedfastingglucoseinmaleworkers |