Genetic landscape of Parkinson’s disease and related diseases in Luxembourg

Genetic landscape of Parkinson’s disease and related diseases in Luxembourg

ObjectivesTo explore the genetic architecture of PD in the Luxembourg Parkinson’s Study including cohorts of healthy people and patients with Parkinson’s disease (PD) and atypical parkinsonism (AP).Methods809 healthy controls, 680 PD and 103 AP were genotyped using the Neurochip array. We screened a...

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Bibliographic Details
Main Authors: Zied Landoulsi, Sinthuja Pachchek, Dheeraj Reddy Bobbili, Lukas Pavelka, Patrick May, Rejko Krüger, the NCER-PD Consortium
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson’s disease
genetics
Luxembourg
polygenic risk score
copy number variants
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1282174/full

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