Superficial acral fibromyxoma: A case report
We report a case of subungual superficial acral fibromyxoma in a 74-year-old woman, who had a subungual neoplasm on the right big toe for 2 months. Dermatological examination revealed a red tumor about 3.0 cm×2.0 cm×1.0 cm in size at the nail bed of the right big toenail and onychomadesis. Ultrasoun...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | zho |
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editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology
2024-02-01
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| Series: | Pifu-xingbing zhenliaoxue zazhi |
| Subjects: | |
| Online Access: | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2024.02.007 |
| _version_ | 1797249379228188672 |
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| author | Yue ZHANG Jinru SONG Ruoyun LIU Liuhong LIU Renliang HE Bin YANG |
| author_facet | Yue ZHANG Jinru SONG Ruoyun LIU Liuhong LIU Renliang HE Bin YANG |
| author_sort | Yue ZHANG |
| collection | DOAJ |
| description | We report a case of subungual superficial acral fibromyxoma in a 74-year-old woman, who had a subungual neoplasm on the right big toe for 2 months. Dermatological examination revealed a red tumor about 3.0 cm×2.0 cm×1.0 cm in size at the nail bed of the right big toenail and onychomadesis. Ultrasound examination of the tumor showed a hypoechoic mass about 21 mm×20 mm in size with an uneven internal echoes of mixed cysts and solids under the right big toe. Digital Radiography of the right foot showed swollen soft tissue of the right big toe, with no changes in bone. Histological changes included epidermal hyperkeratosis and parakeratosis, and partial thickening of spinous layers along with edema of the superficial dermis. There were increases in small blood vessels, fibrous tissue, spindle cells and stellate cells, in addition to perivascular infiltrates of lymphocytes. Alcian blue staining was positive. Immunohistochemistry showed positive for CD34 and Vimentin, and negative for S-100, Desmin, Actin, CD31 and HHV-8. Diagnosis was superficial acral fibromyxoma. The nail bed was healed well after surgical removal of the tumor, and no recurrence was observed. |
| first_indexed | 2024-04-24T20:29:33Z |
| format | Article |
| id | doaj.art-bba7b8fd84d74647ad7cdb0b74bb5d65 |
| institution | Directory Open Access Journal |
| issn | 1674-8468 |
| language | zho |
| last_indexed | 2024-04-24T20:29:33Z |
| publishDate | 2024-02-01 |
| publisher | editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology |
| record_format | Article |
| series | Pifu-xingbing zhenliaoxue zazhi |
| spelling | doaj.art-bba7b8fd84d74647ad7cdb0b74bb5d652024-03-22T02:47:14Zzhoeditoiral office of Journal of Diagnosis and Therapy on Dermato-venereologyPifu-xingbing zhenliaoxue zazhi1674-84682024-02-0131210911210.3969/j.issn.1674-8468.2024.02.007Superficial acral fibromyxoma: A case reportYue ZHANG0Jinru SONG1Ruoyun LIU2Liuhong LIU3Renliang HE4Bin YANG5Guangdong Medical University, Zhanjiang 524023, ChinaDermatology Hospital, Southern Medical University, Guangzhou 510091, ChinaGuangdong Medical University, Zhanjiang 524023, ChinaDermatology Hospital, Southern Medical University, Guangzhou 510091, ChinaDermatology Hospital, Southern Medical University, Guangzhou 510091, ChinaGuangdong Medical University, Zhanjiang 524023, ChinaWe report a case of subungual superficial acral fibromyxoma in a 74-year-old woman, who had a subungual neoplasm on the right big toe for 2 months. Dermatological examination revealed a red tumor about 3.0 cm×2.0 cm×1.0 cm in size at the nail bed of the right big toenail and onychomadesis. Ultrasound examination of the tumor showed a hypoechoic mass about 21 mm×20 mm in size with an uneven internal echoes of mixed cysts and solids under the right big toe. Digital Radiography of the right foot showed swollen soft tissue of the right big toe, with no changes in bone. Histological changes included epidermal hyperkeratosis and parakeratosis, and partial thickening of spinous layers along with edema of the superficial dermis. There were increases in small blood vessels, fibrous tissue, spindle cells and stellate cells, in addition to perivascular infiltrates of lymphocytes. Alcian blue staining was positive. Immunohistochemistry showed positive for CD34 and Vimentin, and negative for S-100, Desmin, Actin, CD31 and HHV-8. Diagnosis was superficial acral fibromyxoma. The nail bed was healed well after surgical removal of the tumor, and no recurrence was observed.http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2024.02.007superficial acral fibromyxomasubungual tumorsurgical resection |
| spellingShingle | Yue ZHANG Jinru SONG Ruoyun LIU Liuhong LIU Renliang HE Bin YANG Superficial acral fibromyxoma: A case report Pifu-xingbing zhenliaoxue zazhi superficial acral fibromyxoma subungual tumor surgical resection |
| title | Superficial acral fibromyxoma: A case report |
| title_full | Superficial acral fibromyxoma: A case report |
| title_fullStr | Superficial acral fibromyxoma: A case report |
| title_full_unstemmed | Superficial acral fibromyxoma: A case report |
| title_short | Superficial acral fibromyxoma: A case report |
| title_sort | superficial acral fibromyxoma a case report |
| topic | superficial acral fibromyxoma subungual tumor surgical resection |
| url | http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2024.02.007 |
| work_keys_str_mv | AT yuezhang superficialacralfibromyxomaacasereport AT jinrusong superficialacralfibromyxomaacasereport AT ruoyunliu superficialacralfibromyxomaacasereport AT liuhongliu superficialacralfibromyxomaacasereport AT renlianghe superficialacralfibromyxomaacasereport AT binyang superficialacralfibromyxomaacasereport |