Nature’s Green Potential: Anticancer Properties of Plants of the Euphorbiaceae Family

The number of cancer cases will reach 24 million in 2040, according to the International Agency for Research on Cancer. Current treatments for cancer are not effective and selective for most patients; for this reason, new anticancer drugs need to be developed and researched enough. There are potenti...

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Main Authors: Víctor Jiménez-González, Tomasz Kowalczyk, Janusz Piekarski, Janusz Szemraj, Patricia Rijo, Przemysław Sitarek
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/16/1/114
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author Víctor Jiménez-González
Tomasz Kowalczyk
Janusz Piekarski
Janusz Szemraj
Patricia Rijo
Przemysław Sitarek
author_facet Víctor Jiménez-González
Tomasz Kowalczyk
Janusz Piekarski
Janusz Szemraj
Patricia Rijo
Przemysław Sitarek
author_sort Víctor Jiménez-González
collection DOAJ
description The number of cancer cases will reach 24 million in 2040, according to the International Agency for Research on Cancer. Current treatments for cancer are not effective and selective for most patients; for this reason, new anticancer drugs need to be developed and researched enough. There are potentially useful drugs for cancer isolated from plants that are being used in the clinic. Available information about phytochemistry, traditional uses, in vitro and in vivo experiments with plants, and pure compounds isolated from the Euphorbiaceae family indicates that this family of plants has the potential to develop anticancer drugs. This review examines selected species from the Euphorbiaceae family and their bioactive compounds that could have potential against different types of cancer cells. It reviews the activity of crude extracts, isolated compounds, and nanoparticles and the potential underlying mechanisms of action.
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spelling doaj.art-bbad366cc90b422791206b159e1152472024-01-10T14:52:43ZengMDPI AGCancers2072-66942023-12-0116111410.3390/cancers16010114Nature’s Green Potential: Anticancer Properties of Plants of the Euphorbiaceae FamilyVíctor Jiménez-González0Tomasz Kowalczyk1Janusz Piekarski2Janusz Szemraj3Patricia Rijo4Przemysław Sitarek5Department of Pharmacology, Faculty of Pharmacy, University of Seville, 41012 Seville, SpainDepartment of Molecular Biotechnology and Genetics, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Lodz, PolandDepartment of Surgical Oncology, Medical University in Lodz, 93-513 Lodz, PolandDepartment of Medical Biochemistry, Medical University of Lodz, 92-215 Lodz, PolandCBIOS-Lusófona University’s Research Center for Biosciences and Health Technologies, 1749-024 Lisbon, PortugalDepartment of Medical Biology, Medical University of Lodz, 90-151 Lodz, PolandThe number of cancer cases will reach 24 million in 2040, according to the International Agency for Research on Cancer. Current treatments for cancer are not effective and selective for most patients; for this reason, new anticancer drugs need to be developed and researched enough. There are potentially useful drugs for cancer isolated from plants that are being used in the clinic. Available information about phytochemistry, traditional uses, in vitro and in vivo experiments with plants, and pure compounds isolated from the Euphorbiaceae family indicates that this family of plants has the potential to develop anticancer drugs. This review examines selected species from the Euphorbiaceae family and their bioactive compounds that could have potential against different types of cancer cells. It reviews the activity of crude extracts, isolated compounds, and nanoparticles and the potential underlying mechanisms of action.https://www.mdpi.com/2072-6694/16/1/114Euphorbiaceae familyin vitroin vivoanticancerextractspure compounds
spellingShingle Víctor Jiménez-González
Tomasz Kowalczyk
Janusz Piekarski
Janusz Szemraj
Patricia Rijo
Przemysław Sitarek
Nature’s Green Potential: Anticancer Properties of Plants of the Euphorbiaceae Family
Cancers
Euphorbiaceae family
in vitro
in vivo
anticancer
extracts
pure compounds
title Nature’s Green Potential: Anticancer Properties of Plants of the Euphorbiaceae Family
title_full Nature’s Green Potential: Anticancer Properties of Plants of the Euphorbiaceae Family
title_fullStr Nature’s Green Potential: Anticancer Properties of Plants of the Euphorbiaceae Family
title_full_unstemmed Nature’s Green Potential: Anticancer Properties of Plants of the Euphorbiaceae Family
title_short Nature’s Green Potential: Anticancer Properties of Plants of the Euphorbiaceae Family
title_sort nature s green potential anticancer properties of plants of the euphorbiaceae family
topic Euphorbiaceae family
in vitro
in vivo
anticancer
extracts
pure compounds
url https://www.mdpi.com/2072-6694/16/1/114
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