The microbiota regulates hematopoietic stem and progenitor cell development by mediating inflammatory signals in the niche

The microbiota regulates hematopoietic stem and progenitor cell development by mediating inflammatory signals in the niche

Summary: The commensal microbiota regulates the self-renewal and differentiation of hematopoietic stem and progenitor cells (HSPCs) in bone marrow. Whether and how the microbiota influences HSPC development during embryogenesis is unclear. Using gnotobiotic zebrafish, we show that the microbiota is...

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Bibliographic Details
Main Authors: Dan Zhong, Haowei Jiang, Chengzhuo Zhou, Abrar Ahmed, Hongji Li, Xiaona Wei, Qiuyu Lian, Melodi Tastemel, Hongyi Xin, Mei Ge, Chenhong Zhang, Lili Jing
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Cell Reports
Subjects:
CP: Microbiology
CP: Stem cell research
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723001274

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