Synthesis and characterization of some new thallium(III) macrocyclic complexes and their biological studies
New symmetrically para-substituted tetraphenylporphyrin Tl(III) salicylate complexes, having the general formula SA/5-SSATl(III)t(4-Y)PP (Y=-H, -CH3, -OCH3); SA=salicylates and 5-SSA=5-sulfosalicylates, were synthesized and characterized by elemental analysis, optical absorption/emission studies, in...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2016-04-01
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| Series: | Main Group Metal Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/mgmc-2015-0027 |
| Summary: | New symmetrically para-substituted tetraphenylporphyrin Tl(III) salicylate complexes, having the general formula SA/5-SSATl(III)t(4-Y)PP (Y=-H, -CH3, -OCH3); SA=salicylates and 5-SSA=5-sulfosalicylates, were synthesized and characterized by elemental analysis, optical absorption/emission studies, infrared spectrum, NMR studies (1H, 205Tl), thermal analysis and mass spectra; the complexes are in good consistency with experimental results. All the newly synthesized complexes exhibited good optical property, and thermogravimetric analysis (TGA) results showed their excellent thermal stability (>400°C). Macrocyclic complexes of Tl(III) ligate to axial ligand to form six-coordinate complex, the nature of which influences the photophysical properties of the former depending upon the spin-orbital coupling character of the axial ligand. A square-based pyramidal structure has been proposed on the basis of these studies. In addition, some of the synthesized complexes of thallium porphyrins were also screened for anti-bacterial activity. Cytotoxic activity of 5-SSATl(III)t (4-OCH3)PP evaluated against four human cancer cell lines exhibited strong (up to 90%) growth inhibition. |
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| ISSN: | 0792-1241 2191-0219 |