Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration.

Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration.

ERp57 (also known as grp58 and PDIA3) is a protein disulfide isomerase that catalyzes disulfide bonds formation of glycoproteins as part of the calnexin and calreticulin cycle. ERp57 is markedly upregulated in most common neurodegenerative diseases downstream of the endoplasmic reticulum (ER) stress...

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Main Authors: Valentina Castillo, Maritza Oñate, Ute Woehlbier, Pablo Rozas, Catherine Andreu, Danilo Medinas, Pamela Valdés, Fabiola Osorio, Gabriela Mercado, René L Vidal, Bredford Kerr, Felipe A Court, Claudio Hetz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4567344?pdf=render

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