Antiarrhythmic Drugs Use in Elderly Patients. Vaughan Williams Class III and IV Drugs
The effectiveness of antiarrhythmic drugs in the elderly is similar to that in younger patients. However data for «the very elderly» are lacking. Elderly patients are more vulnerable to adverse drug reactions (ADRs) because of age-related changes of pharmacokinetics, co-morbidity and drug interactio...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2016-11-01
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| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | https://www.rpcardio.online/jour/article/view/1343 |
| _version_ | 1797232249432702976 |
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| author | E. A. Ushkalova S. K. Zyryanov K. E. Zatolochina A. P. Pereverzev N. A. Chukhareva |
| author_facet | E. A. Ushkalova S. K. Zyryanov K. E. Zatolochina A. P. Pereverzev N. A. Chukhareva |
| author_sort | E. A. Ushkalova |
| collection | DOAJ |
| description | The effectiveness of antiarrhythmic drugs in the elderly is similar to that in younger patients. However data for «the very elderly» are lacking. Elderly patients are more vulnerable to adverse drug reactions (ADRs) because of age-related changes of pharmacokinetics, co-morbidity and drug interactions. Аmioadarone is not considered as the drug of choice in elderly patients because of the high risk of serious ADRs. Other class III drugs should be prescribed to the elderly with great caution under close monitoring of the treatment. Diltiazem and verapamil should not be used in elderly patients with NYHA class III-IV heart failure and should not be combined with β-blockers. |
| first_indexed | 2024-03-08T14:03:23Z |
| format | Article |
| id | doaj.art-bbc13dc95c22401aa60c2c647433fddd |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-04-24T15:57:16Z |
| publishDate | 2016-11-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-bbc13dc95c22401aa60c2c647433fddd2024-04-01T07:43:34ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-11-0112560360910.20996/1819-6446-2016-12-5-603-6091269Antiarrhythmic Drugs Use in Elderly Patients. Vaughan Williams Class III and IV DrugsE. A. Ushkalova0S. K. Zyryanov1K. E. Zatolochina2A. P. Pereverzev3N. A. Chukhareva4People's Friendship University of Russia. Miklukho-Maklaya ul. 6, Moscow, 117198 RussiaPeople's Friendship University of Russia. Miklukho-Maklaya ul. 6, Moscow, 117198 RussiaPeople's Friendship University of Russia. Miklukho-Maklaya ul. 6, Moscow, 117198 RussiaPeople's Friendship University of Russia. Miklukho-Maklaya ul. 6, Moscow, 117198 RussiaScientific Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov. Academika Oparina ul. 4, Moscow, 117997 RussiaThe effectiveness of antiarrhythmic drugs in the elderly is similar to that in younger patients. However data for «the very elderly» are lacking. Elderly patients are more vulnerable to adverse drug reactions (ADRs) because of age-related changes of pharmacokinetics, co-morbidity and drug interactions. Аmioadarone is not considered as the drug of choice in elderly patients because of the high risk of serious ADRs. Other class III drugs should be prescribed to the elderly with great caution under close monitoring of the treatment. Diltiazem and verapamil should not be used in elderly patients with NYHA class III-IV heart failure and should not be combined with β-blockers.https://www.rpcardio.online/jour/article/view/1343class iii and iv antiarrhythmic drugselderly patients |
| spellingShingle | E. A. Ushkalova S. K. Zyryanov K. E. Zatolochina A. P. Pereverzev N. A. Chukhareva Antiarrhythmic Drugs Use in Elderly Patients. Vaughan Williams Class III and IV Drugs Рациональная фармакотерапия в кардиологии class iii and iv antiarrhythmic drugs elderly patients |
| title | Antiarrhythmic Drugs Use in Elderly Patients. Vaughan Williams Class III and IV Drugs |
| title_full | Antiarrhythmic Drugs Use in Elderly Patients. Vaughan Williams Class III and IV Drugs |
| title_fullStr | Antiarrhythmic Drugs Use in Elderly Patients. Vaughan Williams Class III and IV Drugs |
| title_full_unstemmed | Antiarrhythmic Drugs Use in Elderly Patients. Vaughan Williams Class III and IV Drugs |
| title_short | Antiarrhythmic Drugs Use in Elderly Patients. Vaughan Williams Class III and IV Drugs |
| title_sort | antiarrhythmic drugs use in elderly patients vaughan williams class iii and iv drugs |
| topic | class iii and iv antiarrhythmic drugs elderly patients |
| url | https://www.rpcardio.online/jour/article/view/1343 |
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