Hidradenitis suppurativa: an update on connecting the tracts [version 1; referees: 3 approved]

Hidradenitis suppurativa (HS) is a devastating disease involving abscesses, sinus tracts, and inflammation classically affecting the axilla, groin, and/or anogenital region. Although the disease pathogenesis is not fully understood, recent advances suggest that HS pathology runs much deeper than the...

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Main Authors: Mallory K Smith, Cynthia L Nicholson, Angela Parks-Miller, Iltefat H Hamzavi
Format: Article
Language:English
Published: F1000 Research Ltd 2017-07-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-1272/v1
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author Mallory K Smith
Cynthia L Nicholson
Angela Parks-Miller
Iltefat H Hamzavi
author_facet Mallory K Smith
Cynthia L Nicholson
Angela Parks-Miller
Iltefat H Hamzavi
author_sort Mallory K Smith
collection DOAJ
description Hidradenitis suppurativa (HS) is a devastating disease involving abscesses, sinus tracts, and inflammation classically affecting the axilla, groin, and/or anogenital region. Although the disease pathogenesis is not fully understood, recent advances suggest that HS pathology runs much deeper than the cutaneous manifestations. It is now believed that HS is a systemic inflammatory disease that gives rise to the characteristic cutaneous manifestations. This disease is problematic for both patients and physicians to manage because of a variety of diagnostic and management difficulties. This article seeks to provide updates on the current understanding of HS to increase awareness and improve management.
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spelling doaj.art-bbc3c9fadd674096a0647e40308a8e9b2022-12-21T19:50:29ZengF1000 Research LtdF1000Research2046-14022017-07-01610.12688/f1000research.11337.112238Hidradenitis suppurativa: an update on connecting the tracts [version 1; referees: 3 approved]Mallory K Smith0Cynthia L Nicholson1Angela Parks-Miller2Iltefat H Hamzavi3Wayne State University School of Medicine, Detroit, MI, USAHenry Ford Hospital Department of Dermatology, Detroit, MI, USAHenry Ford Hospital Department of Dermatology, Detroit, MI, USAHenry Ford Hospital Department of Dermatology, Detroit, MI, USAHidradenitis suppurativa (HS) is a devastating disease involving abscesses, sinus tracts, and inflammation classically affecting the axilla, groin, and/or anogenital region. Although the disease pathogenesis is not fully understood, recent advances suggest that HS pathology runs much deeper than the cutaneous manifestations. It is now believed that HS is a systemic inflammatory disease that gives rise to the characteristic cutaneous manifestations. This disease is problematic for both patients and physicians to manage because of a variety of diagnostic and management difficulties. This article seeks to provide updates on the current understanding of HS to increase awareness and improve management.https://f1000research.com/articles/6-1272/v1Acne-Like DisordersAntimicrobials & Drug ResistanceCellular Microbiology & PathogenesisCoronary Artery DiseaseDermatologic PathologyEnvironmental MicrobiologyImmunopharmacology & Hematologic PharmacologyInflammatory Bowel DiseaseInnate ImmunityLeukocyte Signaling & Gene ExpressionMedical GeneticsMedical MicrobiologyMusculoskeletal Pharmacology
spellingShingle Mallory K Smith
Cynthia L Nicholson
Angela Parks-Miller
Iltefat H Hamzavi
Hidradenitis suppurativa: an update on connecting the tracts [version 1; referees: 3 approved]
F1000Research
Acne-Like Disorders
Antimicrobials & Drug Resistance
Cellular Microbiology & Pathogenesis
Coronary Artery Disease
Dermatologic Pathology
Environmental Microbiology
Immunopharmacology & Hematologic Pharmacology
Inflammatory Bowel Disease
Innate Immunity
Leukocyte Signaling & Gene Expression
Medical Genetics
Medical Microbiology
Musculoskeletal Pharmacology
title Hidradenitis suppurativa: an update on connecting the tracts [version 1; referees: 3 approved]
title_full Hidradenitis suppurativa: an update on connecting the tracts [version 1; referees: 3 approved]
title_fullStr Hidradenitis suppurativa: an update on connecting the tracts [version 1; referees: 3 approved]
title_full_unstemmed Hidradenitis suppurativa: an update on connecting the tracts [version 1; referees: 3 approved]
title_short Hidradenitis suppurativa: an update on connecting the tracts [version 1; referees: 3 approved]
title_sort hidradenitis suppurativa an update on connecting the tracts version 1 referees 3 approved
topic Acne-Like Disorders
Antimicrobials & Drug Resistance
Cellular Microbiology & Pathogenesis
Coronary Artery Disease
Dermatologic Pathology
Environmental Microbiology
Immunopharmacology & Hematologic Pharmacology
Inflammatory Bowel Disease
Innate Immunity
Leukocyte Signaling & Gene Expression
Medical Genetics
Medical Microbiology
Musculoskeletal Pharmacology
url https://f1000research.com/articles/6-1272/v1
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AT cynthialnicholson hidradenitissuppurativaanupdateonconnectingthetractsversion1referees3approved
AT angelaparksmiller hidradenitissuppurativaanupdateonconnectingthetractsversion1referees3approved
AT iltefathhamzavi hidradenitissuppurativaanupdateonconnectingthetractsversion1referees3approved